Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538611 | 0.92 | HPGD (0.42) | ALDH1A1LMNATP53MAPTKMT2A | |
| SCHEMBL4354226 | 0.91 | KDM4E (0.45) | ALDH1A1NAMPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4533473 | 0.90 | LMNA (0.40) | NAMPTLMNAHPGDCD274CHRM4 | |
| SCHEMBL4529951 | 0.89 | GPR119 (0.46) | ALDH1A1KMT2AMEN1HPGDCD274 | |
| SCHEMBL4538002 | 0.89 | NPY2R (0.42) | NAMPTTP53MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4361277 | 0.89 | MAPK14 (0.40) | NAMPTLMNAMAPK14CD274DRD2 | |
| SCHEMBL4352065 | 0.87 | ALDH1A1 (0.39) | ALDH1A1NAMPTLMNATP53MAPT | |
| SCHEMBL4350134 | 0.87 | CD274 (0.36) | NAMPTLMNAMAPTHPGDCD274 | |
| SCHEMBL4534161 | 0.86 | SCD5 (0.41) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4540400 | 0.86 | GPR119 (0.35) | NAMPTKMT2ASMN1; SMN2MEN1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |