Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 3/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4542868 | 0.96 | EPHX2 (0.46) | EPHX2RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL4533160 | 0.94 | EPHX2 (0.54) | EPHX2RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL4539756 | 0.88 | HDAC3 (0.50) | EPHX2KMT2AALDH1A1 | |
| SCHEMBL4539565 | 0.86 | EPHX2 (0.48) | EPHX2L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL4539751 | 0.85 | ATM (0.50) | L3MBTL1ALDH1A1 | |
| SCHEMBL4542832 | 0.85 | ALDH1A1 (0.54) | EPHX2L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL4538131 | 0.84 | HDAC3 (0.46) | EPHX2KMT2AALDH1A1 | |
| SCHEMBL4532819 | 0.83 | ALDH1A1 (0.49) | EPHX2RAB9AKMT2AALDH1A1USP5 | |
| SCHEMBL4531620 | 0.82 | HSD11B1 (0.58) | EPHX2MEN1KMT2AALDH1A1DCTPP1 | |
| SCHEMBL4542825 | 0.82 | HDAC3 (0.53) | EPHX2L3MBTL1KMT2AALDH1A1USP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | claimed |
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |