Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.80 |
| ▸ | TP53 | P04637 | 3/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10114488 | 0.89 | ALOX15 (1.00) | ALOX15TP53CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10114059 | 0.87 | RXFP1 (0.71) | ALOX15TP53CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10114474 | 0.83 | CYP1A2 (1.00) | ALOX15TP53CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL4533692 | 0.83 | RXFP1 (0.78) | ALOX15TP53CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL12584350 | 0.82 | CYP1A2 (0.78) | ALOX15TP53CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10113906 | 0.82 | RXFP1 (0.84) | ALOX15TP53CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10114499 | 0.82 | TSHR (0.83) | ALOX15TP53CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10114247 | 0.81 | CYP1A2 (0.77) | ALOX15TP53CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10114273 | 0.81 | ALDH1A1 (0.81) | ALOX15TP53CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10114051 | 0.81 | CYP1A2 (0.76) | ALOX15TP53CYP1A2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130303521-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | HYDRA BIOSCIENCES, INC (US) | 2013-11-14 | — | — | US | disclosed |
| US-20130165427-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | HYDRA BIOSCIENCES, INC. (US) | 2013-06-27 | — | — | US | disclosed |
| US-20130059869-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | HYDRA BIOSCIENCES, INC. | 2013-03-07 | — | — | US | disclosed |
| US-20120108614-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | HYDRA BIOSCIENCES, INC. | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108614-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELANE, CASP3, MMP8 | ALOX15 1080/4885TP53 1505/4885CYP1A2 1483/4885 |
| US-20130303521-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELANE, CASP3, MMP8 | ALOX15 1080/4885TP53 1505/4885CYP1A2 1483/4885 |
| US-20130165427-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELANE, CASP3, MMP8 | ALOX15 1080/4885TP53 1505/4885CYP1A2 1483/4885 |
| US-20130059869-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | TRPA1, TRPV1, TRPV3 | ALOX15 148/4885TP53 4574/4885CYP1A2 1369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.