SCHEMBL4533494

SCHEMBL4533494

COc1cccc2c3c(ccc12)OCC1(C3)CC2CCC1C2

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.36
HTR1A P08908 2/20 0.33
HTR2C P28335 1/20 0.33
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20394056 0.85
SCHEMBL4539365 0.76 PNMT (0.37) PNMTHTR1AHTR2CHTR2A
SCHEMBL4609204 0.66 PNMT (0.32) PNMT
SCHEMBL13178141 0.61
SCHEMBL12473426 0.59 CA1 (0.55) PNMT
SCHEMBL357145 0.59 CA1 (0.61) PNMT
SCHEMBL31116611 0.59 CA1 (0.61) PNMT
SCHEMBL3378301 0.58 IMPDH2 (0.35) PNMTHTR1A
SCHEMBL6556521 0.56 CHRM2 (0.40)
Hydrochloric Acid SCHEMBL8603725 0.56 DRD2 (0.61) PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11472943-B2 Polymerizable composition for optical material, optical material, and application thereof MITSUI CHEMICALS, INC. (JP) 2022-10-18 US disclosed
EP-3521322-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS, AND MOLDED BODY MITSUI CHEMICALS INC (JP) 2022-03-09 EP disclosed
US-11248077-B2 Polymerizable composition for optical material and molded product MITSUI CHEMICALS, INC. (JP) 2022-02-15 US disclosed
US-20210054126-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL AND MOLDED PRODUCT MITSUI CHEMICALS, INC. (JP) 2021-02-25 US disclosed
US-20200207947-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND APPLICATION THEREOF MITSUI CHEMICALS, INC. (JP) 2020-07-02 US disclosed
US-20200148856-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, AND MOLDED PRODUCT MITSUI CHEMICALS, INC. (JP) 2020-05-14 US disclosed
EP-3650480-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS AND MOLDED BODY Mitsui Chemicals, Inc. (JP) 2020-05-13 EP disclosed
EP-3029123-B1 PRODUCTION METHOD FOR PHOTOCHROMIC OPTICAL MATERIAL MITSUI CHEMICALS INC (JP) 2019-09-18 EP disclosed
EP-3521322-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS, AND MOLDED BODY Mitsui Chemicals, Inc. (JP) 2019-08-07 EP disclosed
EP-3238903-B1 INTERNAL RELEASE AGENT, COMPOSITION INCLUDING INTERNAL RELEASE AGENT, AND PLASTIC LENS PRODUCTION METHOD USING SAID COMPOSITION MITSUI CHEMICALS INC (JP) 2019-06-19 EP disclosed
EP-0559439-B1 Photochromic composition TOKUYAMA CORP (JP) 1997-06-04 EP disclosed
US-5631382-A PHOTOCHROMIC LENSES TOKUYAMA CORPORATION (JP) 1997-05-20 US disclosed
EP-0773273-A1 PROCESS FOR THE PRODUCTION OF PHOTOCHROMIC PRODUCT OF CURING TOKUYAMA CORPORATION (JP) 1997-05-14 EP disclosed
EP-0773272-A1 PHOTOCHROMIC CURABLE COMPOSITION TOKUYAMA CORPORATION (JP) 1997-05-14 EP disclosed
EP-0696582-A1 Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides TOKUYAMA CORPORATION (JP) 1996-02-14 EP disclosed
US-5462698-A Lenses TOKUYAMA CORPORATION (JP) 1995-10-31 US disclosed
US-5395566-A Addition polymerizable composition, epoxy monomer, imide or anhydride containing fused ring photochromic compound, lenses TOKUYAMA CORPORATION (JP) 1995-03-07 US disclosed
EP-0629626-A2 Cyclopropyl-substituted spiro-photochromic compounds TOKUYAMA CORPORATION (JP) 1994-12-21 EP disclosed
EP-0619358-A1 Photochromic composition TOKUYAMA CORPORATION (JP) 1994-10-12 EP disclosed
EP-0559439-A2 Photochromic composition TOKUYAMA CORPORATION (JP) 1993-09-08 EP disclosed