Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 5/20 | 0.50 |
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27778678 | 0.97 | ATM (0.50) | ATMCES1CES2ESR1CYP19A1 | |
| SCHEMBL6326250 | 0.85 | ESR1 (0.43) | ATMCES1CES2ESR1CYP19A1 | |
| SCHEMBL8603422 | 0.80 | LTA4H (0.53) | LMNAMAPTSMN1; SMN2HTTHPGD | |
| SCHEMBL3298136 | 0.80 | CES1 (0.46) | ATMCES1CES2ESR1L3MBTL1 | |
| SCHEMBL3287793 | 0.80 | CES1 (0.48) | ATMCES1CES2L3MBTL1LMNA | |
| SCHEMBL2767155 | 0.79 | ATM (0.48) | ATMCES1CES2ESR1CYP19A1 | |
| SCHEMBL816510 | 0.79 | CES2 (0.54) | ATMCES1CES2ESR1L3MBTL1 | |
| SCHEMBL1254028 | 0.78 | CES1 (0.44) | ATMCES1CES2ESR1L3MBTL1 | |
| SCHEMBL10738836 | 0.77 | ALDH1A1 (0.58) | L3MBTL1SMN1; SMN2HPGDMEN1ALOX15 | |
| SCHEMBL3281895 | 0.76 | L3MBTL1 (0.44) | ATMCES1CES2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 721 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912953-B1 | PROCESS FOR THE SYNTHESIS OF ROSUVASTATIN CALCIUM | LEK PHARMACEUTICALS (SI) | 2016-08-17 | — | — | EP | claimed |
| CN-102264752-A | Phenylalkyl-imidazole-bisphosphonate compounds | — | 2011-11-30 | — | — | CN | claimed |
| EP-2382223-A1 | PHENYLALKYL-IMIDAZOLE-BISPHOSPHONATE COMPOUNDS | Novartis AG (CH) | 2011-11-02 | — | — | EP | claimed |
| US-20110257131-A1 | PHENYLALKYL-IMIDAZOLE-BISPHOSPHONATE COMPOUNDS | NOVARTIS AG (CH) | 2011-10-20 | — | — | US | claimed |
| WO-2010076258-A1 | PHENYLALKYL-IMIDAZOLE-BISPHOSPHONATE COMPOUNDS | NOVARTIS AG (CH) | 2010-07-08 | — | — | WO | claimed |
| CN-100558689-C | Be used to produce the method for phenol and methyl ethyl ketone | SHELL OIL CO (NL) | 2009-11-11 | — | — | CN | claimed |
| US-7601772-B2 | Nano-composite and method thereof | BRIDGESTONE CORPORATION | 2009-10-13 | — | — | US | claimed |
| WO-2007149842-A2 | METHOD OF PREPARING IMIDAZOLIUM SURFACTANTS | BRIDGESTONE CORPORATION (JP) | 2007-12-27 | — | — | WO | claimed |
| US-20070293684-A1 | Method of preparing imidazolium surfactants | BRIDGESTONE CORPORATION | 2007-12-20 | — | — | US | claimed |
| US-7247687-B2 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-07-24 | — | — | US | claimed |
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | claimed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | claimed |
| US-4968676-A | PLANTS, SOILS, SEEDS | BASF AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | claimed |
| EP-0181293-B1 | PROCESS FOR DYEING SYNTHETIC POLYAMIDE MATERIALS WITH ANTHRACHINONE REACTIVE DYES | CIBA-GEIGY AG (CH) | 1990-10-24 | — | — | EP | claimed |
| EP-0181292-B1 | PROCESS FOR THE CONTINUOUS TRICHROMATIC DYEING OF SYNTHETIC POLYAMIDE MATERIALS | CIBA-GEIGY AG (CH) | 1990-07-25 | — | — | EP | claimed |
| US-4897425-A | Fungicidal cyclohexylamines | BASF AKTIENGESELLSCHAFT (DE) | 1990-01-30 | — | — | US | claimed |
| US-4871761-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-03 | — | — | US | claimed |
| US-4693727-A | Process for dyeing synthetic polyamide materials with fibre-reactive anthraquinone dyes | CIBA-GEIGY CORPORATION (US) | 1987-09-15 | — | — | US | claimed |
| US-4652269-A | Process for the continuous trichromatic dyeing of synthetic polyamide materials: including a blue anthraquinone reactive dye | CIBA-GEIGY CORPORATION (US) | 1987-03-24 | — | — | US | claimed |
| EP-0125093-A1 | Diaz(ep)ine bis(N-amidinoamidine) derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-14 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257131-A1 | PHENYLALKYL-IMIDAZOLE-BISPHOSPHONATE COMPOUNDS | PTEN, INPP5D, PPIP5K2 | ATM 2226/4885CES1 1209/4885CES2 4201/4885 |
| US-20070293684-A1 | Method of preparing imidazolium surfactants | SMARCC2, SMARCC1, ITPR3 | ATM 1122/4885CES1 3093/4885CES2 2583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.