Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | PNMT | P11086 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6638579 | 0.98 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3CHRM2PNMT | |
| SCHEMBL1570054 | 0.82 | TAAR1 (0.54) | SLC6A2SLC6A4SLC6A3CHRM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL14893290 | 0.80 | TAAR1 (0.52) | SLC6A2SLC6A4SLC6A3CHRM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11154524 | 0.80 | TAAR1 (0.52) | SLC6A2SLC6A4SLC6A3CHRM2ALDH1A1 | |
| SCHEMBL8481321 | 0.78 | CHRM2 (0.50) | SLC6A2SLC6A4SLC6A3CHRM2ALDH1A1 | |
| SCHEMBL3842830 | 0.77 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3PNMTDPP4 | |
| SCHEMBL515497 | 0.76 | CHRM2 (0.48) | SLC6A2SLC6A4SLC6A3CHRM2ALDH1A1 | |
| SCHEMBL1146257 | 0.76 | CHRM2 (0.48) | SLC6A2SLC6A4SLC6A3CHRM2ALDH1A1 | |
| SCHEMBL2048982 | 0.76 | CHRM2 (0.48) | SLC6A2SLC6A4SLC6A3CHRM2ALDH1A1 | |
| SCHEMBL2169643 | 0.76 | CHRM2 (0.48) | SLC6A2SLC6A4SLC6A3CHRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773768-B1 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2018-08-22 | — | — | EP | claimed |
| EP-1610779-B1 | 3-OXO-1,3-DIHYDRO-INDAZOLE-2-CARBOXYLIC ACID AMIDE DERIVATIVES AS PHOSPHOLIPASE INHIBITORS | LILLY CO ELI (US) | 2009-09-09 | — | — | EP | claimed |
| EP-1326865-B1 | AZA- AND POLYAZA-NAPHTHALENYL CARBOXAMIDES USEFUL AS HIV INTEGRASE INHIBITORS | MERCK & CO INC (US) | 2009-05-06 | — | — | EP | claimed |
| US-12049461-B2 | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections | GILEAD SCIENCES, INC. (US) | 2024-07-30 | — | — | US | disclosed |
| WO-2023212057-A1 | COMPOSITIONS OF KINETIC NANOPARTICLES CONTAINING NUCLEIC ACIDS, POLYCATIONS AND LIPIDS | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-11-02 | — | — | WO | disclosed |
| US-11566015-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2023-01-31 | — | — | US | disclosed |
| US-20220326230-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | FIRMENICH INCORPORATED (US) | 2022-10-13 | — | — | US | disclosed |
| US-11268952-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | FIRMENICH INCORPORATED (US) | 2022-03-08 | — | — | US | disclosed |
| US-20210276988-A1 | 4,6-DI- AND 2,4,6-TRISUBSTITUTED QUINAZOLINE DERIVATIVES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. | 2021-09-09 | — | — | US | disclosed |
| US-20210238164-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2021-08-05 | — | — | US | disclosed |
| US-10882851-B2 | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections | GILEAD SCIENCES, INC. (US) | 2021-01-05 | — | — | US | disclosed |
| US-5798363-A | Use for tachykinin antagonists to treat emesis | GLAXO GROUP LIMITED (GB) | 1998-08-25 | — | — | US | disclosed |
| US-5792760-A | USEFUL IN TREATMENT OF PSYCHOLOGICAL AND CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| WO-1997038692-A1 | BISINDOLES FOR TREATING PAIN OR NOCICEPTION | ELI LILLY AND COMPANY (US) | 1997-10-23 | — | — | WO | disclosed |
| US-5538982-A | ANTIEMETICS | GLAXO GROUP LIMITED (GB) | 1996-07-23 | — | — | US | disclosed |
| US-5360820-A | Medical use for tachykinin antagonists | GLAXO GROUP LIMITED (GB) | 1994-11-01 | — | — | US | disclosed |
| EP-0533280-A1 | Novel medical use for tachykinin antagonists | GLAXO GROUP LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |
| US-4410532-A | N-Substituted aziridine-2-carboxylic acid derivatives and their immuno-stimulation compositions and methods | BOEHRINGER MANNHEIM GMBH (DE) | 1983-10-18 | — | — | US | disclosed |
| US-4409236-A | N-Substituted aziridine-2-carboxylic acid derivatives and immuno-stimulation composition and method | BOEHRINGER MANNHEIM GMBH (DE) | 1983-10-11 | — | — | US | disclosed |
| US-4321194-A | N-Substituted aziridine-2-carboxylic acid derivatives for immuno stimulation | BOEHRINGER MANNHEIM GMBH (DE) | 1982-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11566015-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | MC3R, MC1R, MC2R | SLC6A2 341/4885SLC6A4 612/4885SLC6A3 524/4885 |
| US-12049461-B2 | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections | NR3C1, NR3C2, NR4A1 | SLC6A2 1606/4885SLC6A4 718/4885SLC6A3 651/4885 |
| US-20210238164-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | MC3R, MC1R, MC2R | SLC6A2 341/4885SLC6A4 612/4885SLC6A3 524/4885 |
| US-20210276988-A1 | 4,6-DI- AND 2,4,6-TRISUBSTITUTED QUINAZOLINE DERIVATIVES USEFUL FOR TREATING VIRAL INFECTIONS | NR3C1, NR3C2, NR4A1 | SLC6A2 1606/4885SLC6A4 718/4885SLC6A3 651/4885 |
| US-20220326230-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | TAS1R2, TAS1R1, TAS2R30 | SLC6A2 1433/4885SLC6A4 407/4885SLC6A3 734/4885 |
| US-10882851-B2 | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections | NR3C1, NR3C2, NR5A2 | SLC6A2 1682/4885SLC6A4 949/4885SLC6A3 688/4885 |
| US-11268952-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | TAS2R40, TAS1R2, TAS1R1 | SLC6A2 1426/4885SLC6A4 366/4885SLC6A3 756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.