Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19949048 | 0.81 | ALDH1A1 (0.30) | — | |
| SCHEMBL8982375 | 0.78 | TP53 (0.32) | KDM4E | |
| SCHEMBL967292 | 0.78 | PGR (0.31) | NPY5RSMN1; SMN2 | |
| SCHEMBL4531420 | 0.75 | CASP1 (0.35) | SMN1; SMN2 | |
| SCHEMBL22341278 | 0.74 | ALDH1A1 (0.33) | SMN1; SMN2 | |
| SCHEMBL969574 | 0.70 | — | — | |
| SCHEMBL497599 | 0.70 | CA12 (0.33) | SMN1; SMN2 | |
| SCHEMBL14065632 | 0.69 | CHRM2 (0.37) | SMN1; SMN2 | |
| SCHEMBL1583466 | 0.69 | SAT1 (0.39) | — | |
| SCHEMBL498168 | 0.69 | CHRM1 (0.36) | NPY5RSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084615-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2011-12-27 | — | — | US | disclosed |
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | UNIVERSITY OF WASHINGTON (US) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, PGLS | KDM4E 4327/4885NPY5R 3877/4885SMN1; SMN2 2296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.