Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13586351 | 0.91 | POLB (0.52) | POLBRAB9AKDM4EMAPTLMNA | |
| SCHEMBL4350134 | 0.91 | CD274 (0.36) | POLBRAB9AKDM4EMAPTLMNA | |
| SCHEMBL4358519 | 0.89 | KDM4E (0.41) | POLBRAB9AKDM4EMAPTLMNA | |
| SCHEMBL4538002 | 0.88 | NPY2R (0.42) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL4351363 | 0.88 | GPR119 (0.46) | POLBRAB9AKDM4EKMT2APKM | |
| SCHEMBL4533473 | 0.87 | LMNA (0.40) | LMNAHPGDGAACD274 | |
| SCHEMBL4540400 | 0.87 | GPR119 (0.35) | KDM4EMEN1KMT2ASMN1; SMN2CD274 | |
| SCHEMBL4361277 | 0.86 | MAPK14 (0.40) | LMNACD274 | |
| SCHEMBL4360517 | 0.86 | NAMPT (0.41) | LMNACD274 | |
| SCHEMBL4532899 | 0.85 | KDM4E (0.36) | POLBRAB9AKDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |