Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4539513 | 0.92 | POLB (0.44) | CD274LMNAPOLBTGM2CHRM4 | |
| SCHEMBL4538200 | 0.91 | POLB (0.42) | CD274LMNAPOLBKDM4EMAPT | |
| SCHEMBL4533473 | 0.89 | LMNA (0.40) | CD274LMNACHRM4HPGDSLC6A2 | |
| SCHEMBL4354303 | 0.89 | KDM4E (0.43) | LMNAKDM4ERAB9A | |
| SCHEMBL4362305 | 0.88 | GPR119 (0.44) | CD274KDM4ERAB9ANAMPT | |
| SCHEMBL4361277 | 0.88 | MAPK14 (0.40) | CD274LMNASLC6A2SLC6A4NAMPT | |
| SCHEMBL4540129 | 0.87 | ALDH1A1 (0.43) | CD274LMNAMAPTCHRM4HPGD | |
| SCHEMBL4538002 | 0.87 | NPY2R (0.42) | CD274MAPTSLC6A4NAMPTHRH3 | |
| SCHEMBL4540400 | 0.85 | GPR119 (0.35) | CD274KDM4ESLC6A4NAMPTHRH3 | |
| SCHEMBL4533472 | 0.85 | KMT2A (0.44) | RAB9ASLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |