Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.44 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | RBP4 | P02753 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | CD38 | P28907 | 1/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30427779 | 0.83 | SSTR4 (0.48) | TRPV1SSTR4CTNNB1WNT3AHSD11B1 | |
| SCHEMBL30427695 | 0.81 | SSTR4 (0.46) | TRPV1SSTR4CTNNB1WNT3AHSD11B1 | |
| SCHEMBL7888808 | 0.81 | SSTR4 (0.46) | MAPTSSTR4CTNNB1WNT3ADHODH | |
| SCHEMBL27936635 | 0.80 | RBP4 (0.45) | TRPV1KDM4ECYP1A2MAPTCTNNB1 | |
| SCHEMBL10161356 | 0.79 | MAPT (0.54) | KDM4ECYP1A2MAPTSSTR4CD38 | |
| SCHEMBL2305519 | 0.78 | EPHX2 (0.44) | SSTR4CTNNB1WNT3ARBP4HSD11B1 | |
| SCHEMBL507101 | 0.78 | ALDH1A1 (0.53) | TRPV1KDM4ESSTR4CTNNB1WNT3A | |
| SCHEMBL28028586 | 0.78 | CACNA1H (0.46) | KDM4ECYP1A2MAPTSSTR4AGBL2 | |
| SCHEMBL10161169 | 0.77 | P2RX7 (0.45) | SSTR4CTNNB1WNT3ARBP4EPHX2 | |
| Hydrochloric Acid SCHEMBL2305254 | 0.77 | ALDH1A1 (0.52) | TRPV1KDM4ESSTR4CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8598176-B2 | Pyridazine compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-12-03 | — | — | US | disclosed |
| US-8258136-B2 | Pyridazine compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-04 | — | — | US | disclosed |
| US-20090275589-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275589-A1 | Pyridazine Compound and Use Thereof | PLPBP, PNPO, PDXK | TRPV1 2363/4885KDM4E 2012/4885CYP1A2 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.