Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4539175 | 0.85 | F13A1 (0.43) | EPHX2ALDH1A1PKMMAPK1NAMPT | |
| Trifluoroacetic Acid SCHEMBL4521875 | 0.73 | TRPV4 (0.40) | KMT2A | |
| SCHEMBL4355670 | 0.71 | TRPV4 (0.38) | KMT2A | |
| SCHEMBL4531768 | 0.70 | KDM1A (0.38) | EPHX2KMT2A | |
| SCHEMBL4349641 | 0.70 | HRH3 (0.47) | ALDH1A1MAPK1KMT2ATSHR | |
| SCHEMBL4540972 | 0.69 | GPR119 (0.47) | KMT2A | |
| SCHEMBL4526460 | 0.67 | SMN1; SMN2 (0.43) | KMT2A | |
| SCHEMBL4360375 | 0.67 | KDM1A (0.39) | ALDH1A1MAPK1TP53KMT2ATSHR | |
| SCHEMBL4534565 | 0.66 | KDM4E (0.40) | EPHX2ALDH1A1TP53KMT2ATSHR | |
| SCHEMBL4356877 | 0.66 | ALDH1A1 (0.45) | ALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |