Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9140532 | 0.94 | HCAR2 (0.37) | HCAR2HCAR3ALDH1A1LMNA | |
| SCHEMBL460418 | 0.78 | MEN1 (0.41) | HCAR2HCAR3MEN1KMT2AALDH1A1 | |
| SCHEMBL5600403 | 0.78 | MEN1 (0.37) | HCAR2HCAR3MEN1KMT2AALDH1A1 | |
| SCHEMBL545497 | 0.76 | ALDH1A1 (0.39) | HCAR2HCAR3MEN1KMT2AKDM4E | |
| SCHEMBL11050350 | 0.76 | MEN1 (0.40) | HCAR2HCAR3MEN1KMT2AALDH1A1 | |
| SCHEMBL5603213 | 0.76 | MEN1 (0.36) | HCAR2HCAR3MEN1KMT2AALDH1A1 | |
| SCHEMBL5601887 | 0.76 | MEN1 (0.36) | HCAR2HCAR3MEN1KMT2AALDH1A1 | |
| SCHEMBL5603360 | 0.76 | MEN1 (0.36) | HCAR2HCAR3MEN1KMT2AALDH1A1 | |
| SCHEMBL5600267 | 0.76 | MEN1 (0.36) | HCAR2HCAR3MEN1KMT2AALDH1A1 | |
| SCHEMBL5600516 | 0.76 | MEN1 (0.36) | HCAR2HCAR3MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946525-B1 | METHOD FOR PRODUCING METAL COMPLEX CARBOXYLIC ACID AMIDES | SCHERING AG (DE) | 2004-04-07 | — | — | EP | claimed |
| US-6045776-A | Process for the production of metal-complex carboxylic acid amides | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-04-04 | — | — | US | claimed |
| US-8263040-B2 | contrast agents for necrosis imaging, diagnosis of changes in the lymphatic system, inflammatory diseases, cardiovascular diseases, tumour imaging; radioactive materials use in radiotherapy | BAYER SCHERING PHARMA AG (DE) | 2012-09-11 | — | — | US | disclosed |
| US-20090297454-A1 | Perfluoroalkyl-Containing Complexes, Process For Their Production As Well As Their Use | SCHIRMER HEIKO | 2009-12-03 | — | — | US | disclosed |
| US-7618957-B2 | 1-N-(Benzyloxycarbonyl)-1H,1H,2H,2H,4H,4H,5H,5H-3-aza-perfluorotridecylamine; used in NMR and x-ray diagnosis, radiodiagnosis, and radiotherapy, as well as in MRT lymphography and in blood-pool imaging | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-11-17 | — | — | US | disclosed |
| EP-2089362-A1 | METAL CHELATES HAVING A PERFLUORINATED PEG GROUP, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-08-19 | — | — | EP | disclosed |
| US-20080159954-A1 | METAL CHELATES HAVING A PERFLUORINATED PEG RADICAL, PROCESSES FOR THEIR PREPARATION, AND THEIR USE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-07-03 | — | — | US | disclosed |
| WO-2008046463-A1 | METAL CHELATES HAVING A PERFLUORINATED PEG GROUP, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-04-24 | — | — | WO | disclosed |
| EP-1904463-A2 | COMPLEXES CONTAINING PERFLUOROALKYL, METHOD FOR THE PRODUCTION AND USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-02 | — | — | EP | disclosed |
| EP-1904462-A2 | COMPLEXES CONTAINING PERFLUOROALKYL, METHOD FOR THE PRODUCTION AND USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-02 | — | — | EP | disclosed |
| US-20070189969-A1 | Perfluoroalkyl-containing complexes, process for their production as well as their use | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-08-16 | — | — | US | disclosed |
| EP-1307236-A2 | USE OF METAL COMPLEXES CONTAINING PERFLUOROALKYL AS CONTRAST AGENTS IN MR-IMAGING FOR THE REPRESENTATION OF PLAQUES, TUMOURS AND NECROSES | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-05-07 | — | — | EP | disclosed |
| US-20030072713-A1 | Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of plaque, tumors and necroses | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2003-04-17 | — | — | US | disclosed |
| US-6461587-B1 | Perfluoroalkylamides, their production and their use in diagnosis | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| WO-2002013874-A2 | USE OF METAL COMPLEXES CONTAINING PERFLUOROALKYL AS CONTRAST AGENTS IN MR-IMAGING FOR THE REPRESENTATION OF PLAQUES, TUMOURS AND NECROSES | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-02-21 | — | — | WO | disclosed |
| EP-1163231-A1 | PERFLUOROALKYLAMIDE, THE PRODUCTION THEREOF AND THE USE THEREOF IN DIAGNOSTICS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000056723-A1 | PERFLUOROALKYLAMIDE, THE PRODUCTION THEREOF AND THE USE THEREOF IN DIAGNOSTICS | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-09-28 | — | — | WO | disclosed |
| US-6045776-A | Process for the production of metal-complex carboxylic acid amides | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-04-04 | — | — | US | disclosed |
| EP-0946525-A1 | METHOD FOR PRODUCING METAL COMPLEX CARBOXYLIC ACID AMIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024775-A1 | METHOD FOR PRODUCING METAL COMPLEX CARBOXYLIC ACID AMIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080159954-A1 | METAL CHELATES HAVING A PERFLUORINATED PEG RADICAL, PROCESSES FOR THEIR PREPARATION, AND THEIR USE | TFRC, FCGRT, SLC39A14 | HCAR2 3526/4885HCAR3 2668/4885MEN1 3381/4885 |
| US-20030072713-A1 | Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of plaque, tumors and necroses | FABP3, PRF1, PTDSS1 | HCAR2 1518/4885HCAR3 1132/4885MEN1 398/4885 |
| US-20070189969-A1 | Perfluoroalkyl-containing complexes, process for their production as well as their use | AFF1, FGB, PF4 | HCAR2 3393/4885HCAR3 3298/4885MEN1 1643/4885 |
| US-20090297454-A1 | Perfluoroalkyl-Containing Complexes, Process For Their Production As Well As Their Use | AFF1, FGB, PF4 | HCAR2 3393/4885HCAR3 3298/4885MEN1 1643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.