Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | ADAMTS1 | Q9UHI8 | 1/20 | 0.36 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3869229 | 0.78 | ADAM17 (0.42) | BMP1MMP1ADAM17ADAMTS4ADAMTS1 | |
| SCHEMBL4542969 | 0.78 | MMP13 (0.41) | BMP1MMP1ADAM17ADAMTS4ADAMTS1 | |
| SCHEMBL4371521 | 0.75 | UTS2R (0.41) | BMP1MMP1ADAM17ADAMTS4ADAMTS1 | |
| SCHEMBL13923480 | 0.74 | BMP1 (0.44) | BMP1MMP1ADAM17ADAMTS4ADAMTS1 | |
| SCHEMBL13791856 | 0.73 | BMP1 (0.48) | BMP1MMP1ADAM17ADAMTS4ADAMTS1 | |
| SCHEMBL1800584 | 0.73 | ADAM17 (0.49) | BMP1MMP1ADAM17ADAMTS4ADAMTS1 | |
| SCHEMBL1802731 | 0.69 | ADAMTS7 (0.44) | MMP1ADAMTS7ADAMTS5 | |
| SCHEMBL1802730 | 0.69 | ADAMTS7 (0.44) | MMP1ADAMTS7ADAMTS5 | |
| SCHEMBL12619375 | 0.67 | ADAM17 (0.49) | BMP1MMP1ADAM17ADAMTS4ADAMTS1 | |
| SCHEMBL1799334 | 0.66 | ADAM17 (0.50) | BMP1MMP1ADAM17ADAMTS4ADAMTS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461313-B1 | HUMAN ADAM-10 INHIBITORS | EXELIXIS INC (US) | 2009-08-05 | — | — | EP | disclosed |