Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537395 | 0.89 | USP30 (0.50) | KMT2AL3MBTL1ALDH1A1GAAMEN1 | |
| SCHEMBL4537192 | 0.88 | ALDH1A1 (0.52) | KMT2AL3MBTL1ALDH1A1LMNAMEN1 | |
| SCHEMBL4540074 | 0.86 | FBP1 (0.50) | KMT2AL3MBTL1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4537525 | 0.86 | EPHX2 (0.50) | KMT2AL3MBTL1ALDH1A1GAAMEN1 | |
| SCHEMBL4541300 | 0.85 | USP30 (0.48) | L3MBTL1ALDH1A1GAA | |
| SCHEMBL4539993 | 0.84 | ALDH1A1 (0.51) | KMT2AL3MBTL1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4542594 | 0.83 | MEN1 (0.47) | KMT2AL3MBTL1ALDH1A1LMNAGAA | |
| SCHEMBL4536853 | 0.83 | EPHX1 (0.49) | KMT2AL3MBTL1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4535924 | 0.82 | ALDH1A1 (0.59) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL4535453 | 0.80 | ALDH1A1 (0.56) | KMT2AL3MBTL1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | claimed |