Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 8/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056993 | 0.86 | PARP10 (0.45) | RBP4FFAR4GPR119 | |
| SCHEMBL4460540 | 0.83 | CHRM4 (0.45) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL3983198 | 0.79 | GPR119 (0.56) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL4050230 | 0.77 | PDE4B (0.45) | — | |
| SCHEMBL4051411 | 0.76 | RBP4 (0.37) | RBP4FFAR4 | |
| SCHEMBL13691391 | 0.76 | GPR119 (0.53) | GPR119 | |
| SCHEMBL4373911 | 0.75 | CLK4 (0.42) | RBP4GPR119 | |
| SCHEMBL4058702 | 0.75 | SLC6A9 (0.49) | GPR119 | |
| SCHEMBL4051573 | 0.74 | CCR5 (0.41) | RBP4 | |
| SCHEMBL4051853 | 0.73 | GPR119 (0.44) | RBP4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106565-A1 | AGONISTS OF GPR119 | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |