Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PKLR | P30613 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | USP5 | P45974 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535854 | 0.88 | KMT2A (0.47) | ALDH1A1SMN1; SMN2L3MBTL1HTTKMT2A | |
| SCHEMBL4530586 | 0.88 | EPHX2 (0.52) | ALDH1A1SMN1; SMN2L3MBTL1HTTKMT2A | |
| SCHEMBL4531162 | 0.88 | KMT2A (0.45) | ALDH1A1SMN1; SMN2L3MBTL1HTTKMT2A | |
| SCHEMBL4534333 | 0.87 | PKM (0.50) | ALDH1A1SMN1; SMN2L3MBTL1HSD17B10KMT2A | |
| SCHEMBL4542832 | 0.87 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL4539847 | 0.85 | USP30 (0.44) | L3MBTL1TDP1 | |
| SCHEMBL4539837 | 0.85 | MEN1 (0.55) | ALDH1A1SMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL4539370 | 0.84 | KMT2A (0.48) | ALDH1A1SMN1; SMN2L3MBTL1HTTHSD17B10 | |
| SCHEMBL4537743 | 0.84 | EPHX2 (0.48) | ALDH1A1SMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL4542446 | 0.82 | SMN1; SMN2 (0.53) | ALDH1A1NPSR1SMN1; SMN2L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | claimed |