Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27643773 | 0.81 | HTR6 (0.39) | OPRD1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4540767 | 0.76 | GPR119 (0.41) | — | |
| SCHEMBL16669939 | 0.72 | PLAT (0.39) | PLATRAB9ASLC6A3KMT2AKDM4E | |
| SCHEMBL16220627 | 0.71 | NPC1 (0.38) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL543803 | 0.70 | ALDH1A1 (0.49) | OPRD1PLATNPC1RAB9AATM | |
| SCHEMBL25446986 | 0.70 | NPC1 (0.42) | NPC1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL27362176 | 0.70 | ALDH1A1 (0.45) | RAB9AATMKDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL544385 | 0.70 | ALDH1A1 (0.48) | OPRD1PLATNPC1RAB9AATM | |
| SCHEMBL34469564 | 0.70 | PLAT (0.40) | OPRD1PLATATMKMT2AKDM4E | |
| SCHEMBL24958725 | 0.70 | PLAT (0.48) | PLATNPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |