Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | ACACA | Q13085 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4543005 | 0.76 | OPRD1 (0.39) | — | |
| SCHEMBL4539192 | 0.72 | DRD2 (0.56) | — | |
| SCHEMBL368619 | 0.70 | GPR119 (0.43) | GPR119CHRM2CHRM1ACACBACACA | |
| SCHEMBL25446986 | 0.70 | NPC1 (0.42) | — | |
| SCHEMBL25446988 | 0.69 | NPC1 (0.41) | — | |
| SCHEMBL19454951 | 0.69 | HSD11B1 (0.44) | GPR119MMP1MMP13MMP3MMP7 | |
| SCHEMBL25478482 | 0.69 | NPC1 (0.42) | CHRM1 | |
| SCHEMBL20762510 | 0.68 | CHRM2 (0.49) | CHRM2CHRM1ACACBACACA | |
| SCHEMBL13617386 | 0.68 | SMN1; SMN2 (0.54) | CHRM2CHRM1MMP1MMP13MMP3 | |
| SCHEMBL20220386 | 0.68 | ADRA1A (0.48) | GPR119ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |