Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | BAX | Q07812 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8129500 | 0.85 | MAPK8 (0.36) | LTA4HMAOBMAPTPTGS2 | |
| SCHEMBL8125843 | 0.85 | KMT2A (0.40) | LTA4HMAOBRAB9APARP10MAPT | |
| SCHEMBL5632254 | 0.82 | LTA4H (0.38) | LTA4HTSHRRAB9APARP10ALDH1A1 | |
| SCHEMBL8115367 | 0.81 | LMNA (0.44) | LTA4HRAB9AALDH1A1TDP1L3MBTL1 | |
| SCHEMBL8130158 | 0.77 | AR (0.45) | TSHRRAB9AALDH1A1 | |
| SCHEMBL162258 | 0.76 | KMT2A (0.33) | MAOBRAB9AMAPTIDO1ALDH1A1 | |
| SCHEMBL1929863 | 0.76 | LTA4H (0.42) | LTA4HTSHRMAOBPARP10MAPT | |
| SCHEMBL11141243 | 0.76 | LTA4H (0.42) | LTA4HTSHRMAOBPARP10MAPT | |
| SCHEMBL1068440 | 0.76 | HSD11B1 (0.33) | MAOBIDO1ALDH1A1POLBTDP1 | |
| SCHEMBL4932041 | 0.76 | LTA4H (0.42) | LTA4HTSHRPARP10TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-B1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2009-12-09 | — | — | EP | claimed |
| EP-1028945-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS ANTI-INFLAMMATORY AGENTS | Amgen Inc. (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999024404-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS ANTI-INFLAMMATORY AGENTS | AMGEN INC. (US) | 1999-05-20 | — | — | WO | disclosed |
| EP-0095683-A1 | Trifluoromethylphenoxyphenyl derivatives, process for their preparation and their use as herbicides | BAYER AG (DE) | 1983-12-07 | — | — | EP | disclosed |
| EP-0095683-A1 | Trifluoromethylphenoxyphenyl derivatives, process for their preparation and their use as herbicides | BAYER AG (DE) | 1983-12-07 | — | — | EP | disclosed |
| US-4414210-A | 2-Hydroxyarylethyltriazole fungicides | ROHM AND HAAS COMPANY (US) | 1983-11-08 | — | — | US | disclosed |
| US-4413003-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1983-11-01 | — | — | US | disclosed |
| EP-0077962-A1 | Derivatives of silicium of trifluoromethylphenoxyphenyl, process for their preparation and their use as herbicides and plant growth regulators | BAYER AG (DE) | 1983-05-04 | — | — | EP | disclosed |
| EP-0077962-A1 | Derivatives of silicium of trifluoromethylphenoxyphenyl, process for their preparation and their use as herbicides and plant growth regulators | BAYER AG (DE) | 1983-05-04 | — | — | EP | disclosed |