Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | BAX | Q07812 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718417 | 0.83 | HTT (0.33) | HPGDNPC1 | |
| SCHEMBL11141243 | 0.80 | LTA4H (0.42) | LTA4HTSHRPARP10NR1H2BAX | |
| SCHEMBL3952656 | 0.80 | PARP10 (0.42) | L3MBTL1FAAHTDP1PARP10SLC6A4 | |
| SCHEMBL8129943 | 0.79 | LMNA (0.47) | LTA4HTDP1HPGDNPC1LMNA | |
| SCHEMBL983525 | 0.78 | TSHR (0.44) | LTA4HTSHRL3MBTL1NR1H2BAX | |
| SCHEMBL1929863 | 0.76 | LTA4H (0.42) | LTA4HTSHRPARP10NR1H2BAX | |
| SCHEMBL7803639 | 0.76 | LTA4H (0.43) | LTA4HTSHRL3MBTL1TDP1PARP10 | |
| SCHEMBL6036733 | 0.76 | LTA4H (0.42) | LTA4HTSHRPARP10NR1H2BAX | |
| SCHEMBL422932 | 0.76 | MAOA (0.43) | LTA4HTSHRPARP10NR1H2BAX | |
| SCHEMBL11140990 | 0.76 | LTA4H (0.42) | LTA4HTSHRPARP10NR1H2BAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37087-E1 | 1-(4-ETHOXYPHENYL)-4-(4-FLUORO-3-PHENOXYPHENYL)-1 -TRIFLUOROMETHYLBUTANE OR 1-(4-ETHOXY-3-FLUOROPHENYL)-4-(3-PHENOXYPHENYL)-1-TRIFLUOROMETHYLBUTANE, FOR EXAMPLE; COMBATS INSECTS AND MITES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | claimed |
| CN-1059669-C | Aryloxycycloalkenyl and aryloxyiminocycloalkenylhydroxyureas | PFIZER (US) | 2000-12-20 | — | — | CN | claimed |
| EP-0790981-B1 | ARYLOXYCYCLOALKENYL AND ARYLOXYIMINOCYCLOALKENYLHYDROXYUREAS AS 5-LIPOXYGENASE INHIBITORS | PFIZER (US) | 1999-09-08 | — | — | EP | claimed |
| US-5798383-A | Aryloxycycloalkenyl and aryloxyiminocycloalkenylhydroxyureas | PFIZER INC. (US) | 1998-08-25 | — | — | US | claimed |
| EP-0790981-A1 | ARYLOXYCYCLOALKENYL AND ARYLOXYIMINOCYCLOALKENYLHYDROXYUREAS AS 5-LIPOXYGENASE INHIBITORS | PFIZER PHARMACEUTICALS INC. (JP) | 1997-08-27 | — | — | EP | claimed |
| CN-1131148-A | Aryloxycycloalkenyl and aryloxyiminocycloalkenylhydroxyureas | PFIZER (US) | 1996-09-18 | — | — | CN | claimed |
| WO-1996015106-A1 | ARYLOXYCYCLOALKENYL AND ARYLOXYIMINOCYCLOALKENYLHYDROXYUREAS AS 5-LIPOXYGENASE INHIBITORS | PFIZER PHARMACEUTICALS INC. (JP) | 1996-05-23 | — | — | WO | claimed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | claimed |
| EP-0233834-B1 | INSECTICIDAL TRIFLUORMETHYL ALKANE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-04-22 | — | — | EP | claimed |
| US-4791123-A | MITICIDES | SCHERING AKT. (DE) | 1988-12-13 | — | — | US | claimed |
| US-4743622-A | FLUORO COMPOUNDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-05-10 | — | — | US | claimed |
| EP-0233834-A1 | Insecticidal trifluormethyl alkane derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-08-26 | — | — | EP | claimed |
| US-4678811-A | INSECTICIDES, MITICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-07-07 | — | — | US | claimed |
| EP-0191723-A1 | Aromatic alkane derivatives, pesticides containing these compounds and processes for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-08-20 | — | — | EP | claimed |
| EP-0179018-A1 | Substituted benzyl ethers, pesticides containing these compounds and processes for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-04-23 | — | — | EP | claimed |
| EP-0136451-A2 | Arylmethyl-ether derivatives, pesticides containing these compounds and process for their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-04-10 | — | — | EP | claimed |
| EP-3236752-A2 | NOVEL ISOTHIAZOLAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102435-A2 | NOVEL ISOTHIAZOLAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-30 | — | — | WO | disclosed |
| US-4414210-A | 2-Hydroxyarylethyltriazole fungicides | ROHM AND HAAS COMPANY (US) | 1983-11-08 | — | — | US | disclosed |
| US-4413003-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1983-11-01 | — | — | US | disclosed |