SCHEMBL1929863

SCHEMBL1929863

Sc1ccc[c]c1Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.42
TSHR P16473 1/20 0.42
NR1H2 P55055 1/20 0.34
BAX Q07812 1/20 0.34
MAOA P21397 1/20 0.34
PARP10 Q53GL7 1/20 0.33
NSD2 O96028 1/20 0.32
HSP90AA1 P07900 1/20 0.32
HKDC1 Q2TB90 1/20 0.32
TLR9 Q9NR96 1/20 0.32
MAOB P27338 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
GAPDH P04406 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GLA P06280 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL983525 0.78 TSHR (0.44) LTA4HTSHRNR1H2BAXKMT2A
SCHEMBL6036733 0.76 LTA4H (0.42) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL11140990 0.76 LTA4H (0.42) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL4932041 0.76 LTA4H (0.42) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL11141243 0.76 LTA4H (0.42) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL422932 0.76 MAOA (0.43) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL7803639 0.76 LTA4H (0.43) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL982444 0.76 LTA4H (0.42) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL4544271 0.76 LTA4H (0.38) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL5919383 0.76 LTA4H (0.38) LTA4HTSHRNR1H2BAXMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2019106-B1 (Thio)Phenoxy Phenyl Silane Composition And Method For Making Same ROHM & HAAS (US) 2013-11-27 EP claimed
US-7956125-B2 (Thio)phenoxy phenyl silane compostion and method for making same ROHM AND HAAS COMPANY (US) 2011-06-07 US claimed
US-20090039313-A1 (Thio)phenoxy phenyl silane compostion and method for making same ROHM AND HAAS COMPANY (US) 2009-02-12 US claimed
EP-2019106-A1 (Thio)Phenoxy Phenyl Silane Composition And Method For Making Same Rohm and Haas Company (US) 2009-01-28 EP claimed
EP-2019106-B1 (Thio)Phenoxy Phenyl Silane Composition And Method For Making Same ROHM & HAAS (US) 2013-11-27 EP disclosed
US-7956125-B2 (Thio)phenoxy phenyl silane compostion and method for making same ROHM AND HAAS COMPANY (US) 2011-06-07 US disclosed
US-20090039313-A1 (Thio)phenoxy phenyl silane compostion and method for making same ROHM AND HAAS COMPANY (US) 2009-02-12 US disclosed
EP-2019106-A1 (Thio)Phenoxy Phenyl Silane Composition And Method For Making Same Rohm and Haas Company (US) 2009-01-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090039313-A1 (Thio)phenoxy phenyl silane compostion and method for making same TPMT, TTR, TST LTA4H 671/4885TSHR 3707/4885NR1H2 3713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.