SCHEMBL454434

SCHEMBL454434

C=CC(C)(O)C(C)CC=C(C)C

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.44
MEN1 O00255 1/20 0.32
CYP3A4 P08684 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11498052 0.81 ALOX15 (0.41) ALOX15
SCHEMBL1302638 0.79 ALOX15 (0.44) ALOX15
SCHEMBL2049118 0.78 ALOX15 (0.35) ALOX15
SCHEMBL301115 0.77 ALOX15 (0.39) ALOX15MEN1CYP3A4KMT2A
SCHEMBL11005598 0.76 ALOX15 (0.41) ALOX15
SCHEMBL3109209 0.76 ALOX15 (0.41) ALOX15
SCHEMBL772676 0.75 MEN1 (0.32) ALOX15MEN1CYP3A4KMT2A
SCHEMBL772677 0.75 MEN1 (0.32) ALOX15MEN1CYP3A4KMT2A
SCHEMBL28553751 0.75 ALOX15 (0.40) ALOX15
SCHEMBL4413348 0.75 ALOX15 (0.40) ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160303019-A1 TOPICAL SKIN CARE FORMULATION MARY KAY INC. 2016-10-20 US claimed
US-9402794-B2 Topical skin care formulation MARY KAY INC. (US) 2016-08-02 US claimed
US-8318222-B2 Topical skin care formulation MARY KAY, INC. (US) 2012-11-27 US claimed
US-8039011-B2 A temperature change composition including a neurosensory component, e.g., menthol, and a first phase change component having a first phase change temperature between 15-40 degrees C., e.g., hydrocarbon, wax; encapsulated evaporative cooling agent; refreshing; durability; receptivity with other skin item KIMBERLY-CLARK WORLDWIDE, INC. (US) 2011-10-18 US claimed
US-20110206793-A1 TOPICAL SKIN CARE FORMULATION MARY KAY INC. (US) 2011-08-25 US claimed
EP-2207524-A2 SKIN COOLING COMPOSITION Kimberly-Clark Worldwide, Inc. (US) 2010-07-21 EP claimed
EP-2059229-A2 SKIN COOLING COMPOSITIONS Kimberly-Clark Worldwide, Inc. (US) 2009-05-20 EP claimed
WO-2009057000-A2 SKIN COOLING COMPOSITION KIMBERLY-CLARK WORLDWIDE, INC. (US) 2009-05-07 WO claimed
US-20090110656-A1 Skin cooling composition KIMBERLY-CLARK WORLDWIDE, INC. 2009-04-30 US claimed
WO-2008044154-A2 SKIN COOLING COMPOSITIONS KIMBERLY-CLARK WORLDWIDE, INC. (US) 2008-04-17 WO claimed
US-20080085290-A1 Skin cooling compositions KIMBERLY-CLARK WORLDWIDE, INC. 2008-04-10 US claimed
US-12605308-B2 Topical skin care formulations comprising plant extracts MARY KAY INC. (US) 2026-04-21 US disclosed
US-20260000603-A1 TOPICAL SKIN CARE FORMULATIONS COMPRISING PLANT EXTRACTS MARY KAY INC. (US) 2026-01-01 US disclosed
EP-4592279-A2 MYELINATION STIMULATOR COMPOUNDS, AND METHODS OF TREATMENT University of Florida Research Foundation, Incorporated (US) 2025-07-30 EP disclosed
EP-3813824-B1 USE OF MYELINATION STIMULATOR COMPOUNDS UNIV FLORIDA (US) 2025-07-02 EP disclosed
EP-2059229-A2 SKIN COOLING COMPOSITIONS Kimberly-Clark Worldwide, Inc. (US) 2009-05-20 EP disclosed
WO-2009057000-A2 SKIN COOLING COMPOSITION KIMBERLY-CLARK WORLDWIDE, INC. (US) 2009-05-07 WO disclosed
US-20090110656-A1 Skin cooling composition KIMBERLY-CLARK WORLDWIDE, INC. 2009-04-30 US disclosed
WO-2008044154-A2 SKIN COOLING COMPOSITIONS KIMBERLY-CLARK WORLDWIDE, INC. (US) 2008-04-17 WO disclosed
US-20080085290-A1 Skin cooling compositions KIMBERLY-CLARK WORLDWIDE, INC. 2008-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260000603-A1 TOPICAL SKIN CARE FORMULATIONS COMPRISING PLANT EXTRACTS CUTA, TYR, FLNA ALOX15 1549/4885MEN1 4738/4885CYP3A4 930/4885
US-12605308-B2 Topical skin care formulations comprising plant extracts MMP9, MMP1, MMP2 ALOX15 267/4885MEN1 3240/4885CYP3A4 310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.