SCHEMBL4546287

SCHEMBL4546287

CC(=O)CCC(=O)O[C@@H]1C(C)O[C@H]2OC(C)(C)OC2[C@H]1C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.33
CA1 P00915 2/20 0.33
CA9 Q16790 2/20 0.33
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.31
GLB1 P16278 1/20 0.30
ABCB1 P08183 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17590140 1.00 CA2 (0.33) CA2CA1CA9ALDH1A1HPGD
SCHEMBL18653832 0.78 ALDH1A1 (0.39) ALDH1A1HPGDABCB1
SCHEMBL13498248 0.74 CA2 (0.42) CA2CA1CA9ALDH1A1HPGD
SCHEMBL13129980 0.73 CA2 (0.41) CA2CA1CA9ALDH1A1HPGD
SCHEMBL13129913 0.73 CA2 (0.41) CA2CA1CA9ALDH1A1HPGD
SCHEMBL15975397 0.73 CA2 (0.38) CA2CA1CA9ALDH1A1HPGD
SCHEMBL2672023 0.73 CA2 (0.60) CA2CA1CA9ALDH1A1HPGD
SCHEMBL17590138 0.72 LGALS8 (0.32) ALDH1A1
SCHEMBL4546316 0.72 LGALS8 (0.32) ALDH1A1
SCHEMBL2672026 0.69 CA2 (0.56) CA2CA1CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987430-B2 Efficient and scalable process for the manufacture of fondaparinux sodium RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2015-03-24 US disclosed
US-20130261291-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2013-10-03 US disclosed
US-20130102764-A1 PROCESS FOR PERPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2013-04-25 US disclosed
US-8420790-B2 Efficient and scalable process for the manufacture of Fondaparinux sodium RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2013-04-16 US disclosed
US-8288515-B2 Process for preparing Fondaparinux sodium and intermediates useful in the synthesis thereof RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2012-10-16 US disclosed
US-20120116066-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2012-05-10 US disclosed
US-20110105418-A1 PROCESS FOR PREPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2011-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105418-A1 PROCESS FOR PREPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF F11, TFPI, STS CA2 1106/4885CA1 638/4885CA9 633/4885
US-20130102764-A1 PROCESS FOR PERPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF TFPI, PLG, PCSK6 CA2 1018/4885CA1 776/4885CA9 445/4885
US-20120116066-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM F11, F10, F2 CA2 519/4885CA1 817/4885CA9 465/4885
US-20130261291-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM F11, F10, F2 CA2 519/4885CA1 817/4885CA9 465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.