SCHEMBL4546316

SCHEMBL4546316

CC(=O)CCC(=O)O[C@@H]1C(C)O[C@@H](O)C(O)[C@H]1C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 2/20 0.32
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17590138 1.00 LGALS8 (0.32) LGALS8ALDH1A1MAPT
SCHEMBL4546306 0.76 LGALS9 (0.40)
SCHEMBL17590139 0.76 LGALS9 (0.40)
SCHEMBL2786775 0.74 LGALS8 (0.43) LGALS8MAPT
SCHEMBL4546287 0.72 CA2 (0.33) ALDH1A1
SCHEMBL12807125 0.71 LGALS8 (0.39) LGALS8
SCHEMBL1971069 0.70 PDPK1 (0.39) LGALS8ALDH1A1
SCHEMBL16019242 0.70 LGALS8 (0.42) LGALS8
SCHEMBL23855309 0.69 MAPT (0.40) ALDH1A1MAPT
SCHEMBL22033788 0.69 MAPT (0.40) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987430-B2 Efficient and scalable process for the manufacture of fondaparinux sodium RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2015-03-24 US disclosed
US-20130261291-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2013-10-03 US disclosed
US-20130102764-A1 PROCESS FOR PERPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2013-04-25 US disclosed
US-8420790-B2 Efficient and scalable process for the manufacture of Fondaparinux sodium RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2013-04-16 US disclosed
US-8288515-B2 Process for preparing Fondaparinux sodium and intermediates useful in the synthesis thereof RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2012-10-16 US disclosed
US-20120116066-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2012-05-10 US disclosed
US-20110105418-A1 PROCESS FOR PREPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2011-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105418-A1 PROCESS FOR PREPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF F11, TFPI, STS LGALS8 2654/4885ALDH1A1 3144/4885MAPT 4844/4885
US-20130102764-A1 PROCESS FOR PERPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF TFPI, PLG, PCSK6 LGALS8 2126/4885ALDH1A1 2876/4885MAPT 4860/4885
US-20120116066-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM F11, F10, F2 LGALS8 3253/4885ALDH1A1 2360/4885MAPT 4794/4885
US-20130261291-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM F11, F10, F2 LGALS8 3253/4885ALDH1A1 2360/4885MAPT 4794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.