SCHEMBL4548626

SCHEMBL4548626

CC(C)(C)c1ccc2c(C(C)(C)C)cccc2n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.39
BACE1 P56817 2/20 0.36
GPR3 P46089 1/20 0.35
ATM Q13315 1/20 0.35
ELANE P08246 1/20 0.35
AR P10275 1/20 0.35
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
ALDH1A1 P00352 5/20 0.34
HMGCR P04035 1/20 0.34
TSHR P16473 2/20 0.33
MAPT P10636 2/20 0.33
PLA2G1B P04054 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KIF11 P52732 1/20 0.33
CCR4 P51679 1/20 0.33
HPGD P15428 2/20 0.32
HSD17B10 Q99714 2/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29378537 1.00 CA2 (0.39) CA2BACE1GPR3ATMELANE
SCHEMBL17516297 0.81 ALDH1A1 (0.49) CA2GPR3ARGABRA1GABRB2
SCHEMBL26523061 0.79 CA2 (0.47) CA2BACE1ATMELANEAR
SCHEMBL15614881 0.79 CA2 (0.38) CA2BACE1ATMELANEAR
SCHEMBL13666780 0.79 PDE10A (0.39) GPR3ATMELANEALDH1A1HMGCR
SCHEMBL22768285 0.78 HMGCR (0.41) GPR3ATMELANEGABRA1GABRB2
SCHEMBL23919954 0.77 HMGCR (0.46) BACE1GPR3ATMELANEALDH1A1
SCHEMBL12403549 0.77 RAB9A (0.45) ARALDH1A1HPGDCYP1A2NPC1
SCHEMBL20047599 0.77 CCR4 (0.39) CA2GPR3ATMELANEGABRA1
SCHEMBL19285964 0.77 CA2 (0.35) CA2BACE1ATMELANEAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118105531-A Hydrocolloid dressing, arteriovenous internal fistula wound dressing and application thereof 大连医科大学附属第二医院 2024-05-31 CN claimed
CN-111501204-B Comfortable protective gloves and preparation method thereof 陈美荷 2022-02-11 CN claimed
CN-109395155-B Silver-containing medical hydrocolloid dressing and preparation method thereof Henan Huibo Medical Co.,Ltd. (CN) 2021-06-22 CN claimed
CN-111501204-A Comfortable protective gloves and preparation method thereof 陈美荷 2020-08-07 CN claimed
CN-110982453-A Rubber type water-based pressure-sensitive adhesive and preparation method and application thereof 无锡达美新材料有限公司 2020-04-10 CN claimed
CN-109395155-A A kind of argentiferous medical use hydrocolloid dressing and preparation method thereof 河南汇博医疗股份有限公司 2019-03-01 CN claimed
CN-108926428-A Hydrocolloid applies core and preparation method thereof, bearing hydrocolloid dressing and application thereof 河南汇博医疗股份有限公司 2018-12-04 CN claimed
CN-108186197-A A kind of complex function dressing for preventing and treating pressure sore and preparation method thereof 河南汇博医疗股份有限公司 2018-06-22 CN claimed
CN-118105531-A Hydrocolloid dressing, arteriovenous internal fistula wound dressing and application thereof 大连医科大学附属第二医院 2024-05-31 CN disclosed
US-11446389-B2 Maytansinoid derivatives, conjugates thereof, and methods of use REGENERON PHARMACEUTICALS, INC. (US) 2022-09-20 US disclosed
US-20220259225-A1 Maytansinoid Derivatives, Conjugates Thereof, and Methods of Use REGENERON PHARMACEUTICALS, INC. 2022-08-18 US disclosed
CN-111501204-B Comfortable protective gloves and preparation method thereof 陈美荷 2022-02-11 CN disclosed
CN-110982453-B Rubber type water-based pressure-sensitive adhesive and preparation method and application thereof 广东创阳新材料科技有限公司 2021-08-10 CN disclosed
CN-108926428-B Hydrocolloid dressing core and preparation method thereof, hydrocolloid dressing and application thereof 河南汇博医疗股份有限公司 2021-07-30 CN disclosed
US-5868913-A COATING BY PHYSICAL VAPOR DEPOSITION OF A MIXTURE OF RUTHENIUM OXIDE, AND AT LEAST ONE NON-NOBLE METAL OXIDE IN A SYSTEM CHARGED WITH OXYGEN AND HEAT TREATING THE COATED SUBSTRATE; IMPROVED DURABILITY ANODE FOR ELECTROLYTIC CELL IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1999-02-09 US disclosed
EP-0724656-A1 ELECTRODE AND PREPARATION THEREOF IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1996-08-07 EP disclosed
WO-1995005499-A1 ELECTRODE AND PREPARATION THEREOF IMPERIAL CHEMICAL INDUSTRIES (GB) 1995-02-23 WO disclosed
US-4975272-A A MIXTURE OF SUNSCREEN AND AN ESTERIFIED, OIL-SOLUBLE, PHENOLIC LATENT OXIDATION INHIBITOR VOYT WALTER F (US) 1990-12-04 US disclosed
EP-0100793-B1 AQUEOUS DISPERSIONS COMPRISING COLLOIDAL SIZED PARTICLES OF A POLYMER AND AN ADDITIVE AND A METHOD FOR THEIR PREPARATION THE DOW CHEMICAL COMPANY (US) 1986-10-15 EP disclosed
EP-0100793-A1 Aqueous dispersions comprising colloidal sized particles of a polymer and an additive and a method for their preparation THE DOW CHEMICAL COMPANY (US) 1984-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11446389-B2 Maytansinoid derivatives, conjugates thereof, and methods of use HNMT, SLC10A1, SLC10A2 CA2 3463/4885BACE1 2766/4885GPR3 1051/4885
US-20220259225-A1 Maytansinoid Derivatives, Conjugates Thereof, and Methods of Use SLC10A1, HNMT, OGFR CA2 3421/4885BACE1 2920/4885GPR3 1159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.