Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | GCGR | P47871 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10773642 | 0.78 | RAB9A (0.59) | KDM1AMAOAMAOBGCGRNPC1 | |
| SCHEMBL10522610 | 0.78 | RAB9A (0.59) | KDM1AMAOAMAOBGCGRNPC1 | |
| SCHEMBL20968353 | 0.77 | NPC1 (0.55) | KDM1AMAOAMAOBGCGRNPC1 | |
| SCHEMBL19283328 | 0.77 | KDM1A (0.70) | KDM1AMAOAMAOBGCGRNPC1 | |
| SCHEMBL19283329 | 0.77 | KDM1A (0.70) | KDM1AMAOAMAOBGCGRNPC1 | |
| SCHEMBL6569742 | 0.77 | KDM1A (0.79) | KDM1AMAOAMAOBGCGRNPC1 | |
| SCHEMBL6569739 | 0.77 | KDM1A (0.79) | KDM1AMAOAMAOBGCGRNPC1 | |
| SCHEMBL28528684 | 0.77 | SIRT1 (0.80) | KDM1AMAOAMAOBGCGRNPC1 | |
| SCHEMBL20968356 | 0.76 | GCGR (0.52) | KDM1AMAOAMAOBGCGRNPC1 | |
| SCHEMBL20968393 | 0.75 | NPC1 (0.56) | GCGRNPC1RAB9ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421613-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF | The Procter & Gamble Company (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-2421501-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | The Procter & Gamble Company (US) | 2012-02-29 | — | — | EP | disclosed |
| US-8034128-B2 | Thickened hair colourant and bleaching compositions | THE PROCTER & GAMBLE COMPANY (US) | 2011-10-11 | — | — | US | disclosed |
| US-8034127-B2 | Thickened hair colourant and bleaching compositions | THE PROCTER & GAMBLE COMPANY (US) | 2011-10-11 | — | — | US | disclosed |
| US-8029578-B2 | Thickened hair colourant and bleaching compositions | THE PROCTER & GAMBLE COMPANY (US) | 2011-10-04 | — | — | US | disclosed |
| US-8002850-B2 | Powdered hair coloring and bleaching compositions | THE PROCTER & GAMBLE COMPANY (US) | 2011-08-23 | — | — | US | disclosed |
| US-7988740-B2 | Keratin dyeing compositions comprising a radical scavenger and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2011-08-02 | — | — | US | disclosed |
| US-7985266-B2 | Keratin dyeing compositions comprising a radical scavenger and a chelant and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2011-07-26 | — | — | US | disclosed |
| US-20110168201-A1 | THICKENED HAIR COLOURANT AND BLEACHING COMPOSITIONS | WELLA OPERATIONS US, LLC | 2011-07-14 | — | — | US | disclosed |
| WO-2011085140-A1 | THICKENED HAIR COLOURANT AND BLEACHING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2011-07-14 | — | — | WO | disclosed |
| WO-2011034802-A1 | THICKENED HAIR COLOURANT AND BLEACHING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2011-03-24 | — | — | WO | disclosed |
| US-20110067722-A1 | Thickened Hair Colourant and Bleaching Compositions | WELLA OPERATIONS US, LLC | 2011-03-24 | — | — | US | disclosed |
| US-20110067723-A1 | Thickened Hair Colourant and Bleaching Compositions | WELLA OPERATIONS US, LLC | 2011-03-24 | — | — | US | disclosed |
| WO-2011034868-A1 | THICKENED HAIR COLOURANT AND BLEACHING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2011-03-24 | — | — | WO | disclosed |
| EP-2298417-A1 | Thickened hair colourant and bleaching compositions | The Procter & Gamble Company (US) | 2011-03-23 | — | — | EP | disclosed |
| US-20110035885-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and Use Thereof | NOXELL CORPORATION | 2011-02-17 | — | — | US | disclosed |
| US-20110035886-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof | NOXELL CORPORATION | 2011-02-17 | — | — | US | disclosed |
| EP-2274286-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | The Procter & Gamble Company (US) | 2011-01-19 | — | — | EP | disclosed |
| US-7288123-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-10-30 | — | — | US | disclosed |
| US-20060042024-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | NOXELL CORPORATION | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060042024-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, NOX5, JUP | KDM1A 457/4885MAOA 435/4885MAOB 896/4885 |
| US-20110035885-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and Use Thereof | KRT18, LPO, CYB5R3 | KDM1A 472/4885MAOA 385/4885MAOB 625/4885 |
| US-20110035886-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof | KRT18, LPO, KRTCAP2 | KDM1A 214/4885MAOA 400/4885MAOB 752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.