Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.34 |
| ▸ | FEN1 | P39748 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13000140 | 0.95 | TDP2 (0.37) | PTGS2NAAAHTR2CTDP2PTGS1 | |
| SCHEMBL13000413 | 0.90 | CCNT1 (0.32) | PTGS2PTGS1CCNT1CDK9 | |
| SCHEMBL170384 | 0.87 | CCNT1 (0.34) | CCNT1CDK9 | |
| SCHEMBL12018685 | 0.85 | CCNT1 (0.38) | ALOX5APFEN1PTGS2NAAAHTR2C | |
| SCHEMBL13000117 | 0.84 | NAAA (0.37) | NAAACCNT1CDK9 | |
| SCHEMBL172357 | 0.84 | AKR1C3 (0.33) | — | |
| SCHEMBL12999891 | 0.84 | NAAA (0.34) | PTGS2NAAATDP2PTGS1CCNT1 | |
| SCHEMBL13000112 | 0.82 | NAAA (0.31) | NAAA | |
| SCHEMBL8938629 | 0.82 | — | — | |
| SCHEMBL20614206 | 0.81 | GRM2 (0.36) | ALOX5APFEN1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8945420-B2 | Liquid crystal display and liquid crystalline medium | MERCK PATENT GMBH (DE) | 2015-02-03 | — | — | US | disclosed |
| US-8945420-B2 | Liquid crystal display and liquid crystalline medium | MERCK PATENT GMBH (DE) | 2015-02-03 | — | — | US | disclosed |
| US-20120307177-A1 | LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-06 | — | — | US | disclosed |
| EP-2239310-B1 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2012-06-27 | — | — | EP | disclosed |
| US-8202584-B2 | Liquid-crystalline medium and liquid-crystal display | MERCK PATENT GMBH (DE) | 2012-06-19 | — | — | US | disclosed |
| US-8168081-B2 | Liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-05-01 | — | — | US | disclosed |
| US-8043671-B2 | Liquid-crystalline medium and liquid crystal display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-10-25 | — | — | US | disclosed |
| WO-2011098202-A1 | LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2011-08-18 | — | — | WO | disclosed |
| US-20110101270-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-05-05 | — | — | US | disclosed |
| EP-2239310-A1 | Liquid crystal medium and liquid crystal display | Merck Patent GmbH (DE) | 2010-10-13 | — | — | EP | disclosed |
| US-20100252777-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-10-07 | — | — | US | disclosed |
| EP-2199362-A2 | Liquid crystalline medium | Merck Patent GmbH (DE) | 2010-06-23 | — | — | EP | disclosed |
| WO-2010057575-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2010-05-27 | — | — | WO | disclosed |
| US-20100108945-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-05-06 | — | — | US | disclosed |
| EP-2182046-A1 | Liquid-crystalline medium and liquid crystal display | Merck Patent GmbH (DE) | 2010-05-05 | — | — | EP | disclosed |
| US-20090309066-A1 | Mixture of polar compounds containing cyclohexane and benzene rings some of which are vinylene-linked, especially containing fluoroalkoxy groups; for electrooptical twisted nematic monitor applications | MERCK PATENT GESELLSCHAFT (DE) | 2009-12-17 | — | — | US | disclosed |
| WO-2009129911-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH, (DE) | 2009-10-29 | — | — | WO | disclosed |
| WO-2009115186-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2009-09-24 | — | — | WO | disclosed |
| WO-2008009417-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120307177-A1 | LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTALLINE MEDIUM | CUTA, NEFM, FES | ALOX5AP 3597/4885FEN1 2817/4885PTGS2 3795/4885 |
| US-20090309066-A1 | Mixture of polar compounds containing cyclohexane and benzene rings some of which are vinylene-linked, especially containing fluoroalkoxy groups; for electrooptical twisted nematic monitor applications | VIM, CDH1, LEF1 | ALOX5AP 3325/4885FEN1 443/4885PTGS2 3962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.