Sugi Predict

Sugi Predict / Compounds / SCHEMBL4549947

SCHEMBL4549947

SCHEMBL4549947

CC(C)(C)OC(=O)NC1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AAK1 Q2M2I8 2/20 0.49
▸ PRMT5 O14744 1/20 0.44
▸ WDR77 Q9BQA1 1/20 0.44
▸ USP30 Q70CQ3 1/20 0.42
▸ DGAT1 O75907 1/20 0.39
▸ AKT1 P31749 1/20 0.39
▸ P4HB P07237 1/20 0.38
▸ F2 P00734 1/20 0.38
▸ F11 P03951 1/20 0.38
▸ PRSS1 P07477 1/20 0.38
▸ PRSS2 P07478 1/20 0.38
▸ PRSS3 P35030 1/20 0.38
▸ CA1 P00915 3/20 0.37
▸ CA2 P00918 3/20 0.37
▸ CA9 Q16790 3/20 0.37
▸ CA12 O43570 1/20 0.37
▸ CA3 P07451 1/20 0.37
▸ CA4 P22748 1/20 0.37
▸ CA6 P23280 1/20 0.37
▸ CA5A P35218 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1142034 0.95 AAK1 (0.47) AAK1PRMT5WDR77USP30DGAT1
SCHEMBL361565 0.95 AAK1 (0.47) AAK1PRMT5WDR77USP30DGAT1
SCHEMBL10215891 0.90 AAK1 (0.47) AAK1PRMT5WDR77USP30DGAT1
SCHEMBL15401660 0.90 AAK1 (0.47) AAK1PRMT5WDR77USP30DGAT1
SCHEMBL15276604 0.90 AAK1 (0.47) AAK1PRMT5WDR77USP30DGAT1
SCHEMBL2755130 0.90 AAK1 (0.47) AAK1PRMT5WDR77USP30DGAT1
SCHEMBL10226761 0.89 AAK1 (0.49) AAK1PRMT5WDR77USP30DGAT1
SCHEMBL12133462 0.89 AAK1 (0.47) AAK1PRMT5WDR77USP30DGAT1
SCHEMBL16936500 0.89 USP30 (0.49) AAK1PRMT5WDR77USP30AKT1
SCHEMBL251158 0.88 AAK1 (0.46) AAK1PRMT5WDR77USP30DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630554-B2 Pyrimidinone compounds and uses thereof HUTCHISON MEDIPHARMA LIMITED (CN) 2026-05-19 — — US disclosed
US-12168057-B2 IRAK degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2024-12-17 — — US disclosed
US-20240226107-A1 UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR HAINAN SIMCERE ZAIMING PHARMACEUTICAL CO., LTD. (CN) 2024-07-11 — — US disclosed
US-20240226107-A1 UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR HAINAN SIMCERE ZAIMING PHARMACEUTICAL CO., LTD. (CN) 2024-07-11 — — US disclosed
US-20240199651-A1 ANTIBACTERIAL COMPOUNDS Janssen Sciences Ireland Unlimited Company (IE) 2024-06-20 — — US disclosed
US-20240182495-A1 ANTIBACTERIAL COMPOUNDS Janssen Sciences Ireland Unlimited Company (IE) 2024-06-06 — — US disclosed
CN-117580843-A Antibacterial compounds 爱尔兰詹森科学公司 2024-02-20 — — CN disclosed
EP-4321515-A1 UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR Simcere Zaiming Pharmaceutical Co., Ltd. (CN) 2024-02-14 — — EP disclosed
EP-4308238-A1 ANTIBACTERIAL COMPOUNDS Janssen Sciences Ireland Unlimited Company (IE) 2024-01-24 — — EP disclosed
EP-4308579-A1 ANTIBACTERIAL COMPOUNDS Janssen Sciences Ireland Unlimited Company (IE) 2024-01-24 — — EP disclosed
US-9145355-B2 Phenicol antibacterials ZOETIS SERVICES LLC (US) 2015-09-29 — — US disclosed
US-20140303384-A1 NOVEL PHENICOL ANTIBACTERIALS ZOETIS SERVICES LLC 2014-10-09 — — US disclosed
US-8569331-B2 Substituted benzo[f]lmidazo[1,2-d]pyrido[2,3-b][1,4]diazepine compounds ARQULE, INC. (US) 2013-10-29 — — US disclosed
US-8569331-B2 Substituted benzo[f]lmidazo[1,2-d]pyrido[2,3-b][1,4]diazepine compounds ARQULE, INC. (US) 2013-10-29 — — US disclosed
US-20130184273-A1 BICYCLIC PYRIMIDINES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-07-18 — — US disclosed
US-20130184273-A1 BICYCLIC PYRIMIDINES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-07-18 — — US disclosed
WO-2013057619-A1 NOVEL PHENICOL ANTIBACTERIALS AH USA 42 LLC (US) 2013-04-25 — — WO disclosed
WO-2012061342-A2 SUBSTITUTED BENZO-IMIDAZO-PYRIDO-DIAZEPINE COMPOUNDS ARQULE, INC. (US) 2012-05-10 — — WO disclosed
US-20120108574-A1 Substituted Benzo-Imidazo-Pyrido-Diazepine Compounds ARQULE, INC. (US) 2012-05-03 — — US disclosed
WO-2012007416-A1 BICYCLIC PYRIMIDINES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2012-01-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199651-A1 ANTIBACTERIAL COMPOUNDS FDPS, MT-ND4, NDUFS3 AAK1 4252/4885PRMT5 2267/4885WDR77 3649/4885
US-20240226107-A1 UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR USP1, USP2, USP3 AAK1 1013/4885PRMT5 1637/4885WDR77 286/4885
US-20130184273-A1 BICYCLIC PYRIMIDINES PIK3CA, TYMS, PIK3CD AAK1 1049/4885PRMT5 2259/4885WDR77 1249/4885
US-20120108574-A1 Substituted Benzo-Imidazo-Pyrido-Diazepine Compounds BRD4, BRPF3, BRD3 AAK1 3440/4885PRMT5 2041/4885WDR77 3136/4885
US-20240182495-A1 ANTIBACTERIAL COMPOUNDS FDPS, MT-ND4, NDUFS3 AAK1 4252/4885PRMT5 2267/4885WDR77 3649/4885
US-20140303384-A1 NOVEL PHENICOL ANTIBACTERIALS MRPL21, CTSL, TTL AAK1 3589/4885PRMT5 3212/4885WDR77 944/4885
US-12168057-B2 IRAK degraders and uses thereof IRAK2, IRAK3, IRAK1 AAK1 1009/4885PRMT5 1914/4885WDR77 158/4885
US-12630554-B2 Pyrimidinone compounds and uses thereof CYP2D6, TPMT, CYP2B6 AAK1 3796/4885PRMT5 514/4885WDR77 1848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.