Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 7/20 | 1.00 |
| ▸ | SLC5A2 | P31639 | 7/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.77 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.77 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.77 |
| ▸ | RELA | Q04206 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | TTR | P02766 | 1/20 | 0.77 |
| ▸ | ESR1 | P03372 | 1/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phloretin SCHEMBL27817019 | 0.92 | SLC5A1 (0.87) | SLC5A1SLC5A2GAAMAPTCYP19A1 | |
| Phloretin SCHEMBL21192491 | 0.88 | SLC5A1 (0.87) | SLC5A1SLC5A2GAAMAPTCYP19A1 | |
| Phloretin SCHEMBL38131 | 0.87 | SLC5A1 (1.00) | SLC5A1SLC5A2GAAMAPTCYP19A1 | |
| Phloretin SCHEMBL1506325 | 0.87 | SLC5A1 (1.00) | SLC5A1SLC5A2GAAMAPTCYP19A1 | |
| SCHEMBL4742840 | 0.87 | NFKB1 (0.80) | SLC5A1SLC5A2GAAMAPTCYP19A1 | |
| SCHEMBL19668159 | 0.86 | SLC5A1 (0.76) | SLC5A1SLC5A2GAAMAPTCYP19A1 | |
| SCHEMBL30913242 | 0.86 | SLC5A1 (0.76) | SLC5A1SLC5A2GAAMAPTCYP19A1 | |
| Phloretin SCHEMBL30785809 | 0.86 | SLC5A1 (0.96) | SLC5A1SLC5A2GAAMAPTCYP19A1 | |
| Phloretin SCHEMBL30912872 | 0.86 | SLC5A1 (0.96) | SLC5A1SLC5A2GAAMAPTCYP19A1 | |
| Phloretin SCHEMBL31684375 | 0.86 | SLC5A1 (0.96) | SLC5A1SLC5A2GAAMAPTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10695283-B2 | Extract of Greyia radlkoferi and use thereof | UNIVERSITY OF PRETORIA (ZA) | 2020-06-30 | — | — | US | claimed |
| US-20180071204-A1 | EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2018-03-15 | — | — | US | claimed |
| EP-2849768-B1 | EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF | UNIV PRETORIA (ZA) | 2016-06-01 | — | — | EP | claimed |
| US-20150118337-A1 | EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF | UNIVERSITY OF PRETORIA (ZA) | 2015-04-30 | — | — | US | claimed |
| US-20110256115-A1 | HYDROSOLUBLE [6)O-ALPHA-D-GLCP-(1->]N-6-O-BETA-D-GLCP-(1->-PHENOLIC DERIVATIVES WITH DERMOCOSMETIC, NUTRITIONAL AND THERAPEUTIC APPLICATIONS, AND COMPOSITIONS CONTAINING SAID WATER SOLUBLE COMPOUNDS | LIBRAGEN (FR) | 2011-10-20 | — | — | US | claimed |
| EP-2202237-A1 | Hydrosoluble [6)-O-alpha-d-glcp-(1->]n-6-o-bêta-d-glcp-(1->-phenllic derivatives with dermocosmetic, nutritional and therapeutic applications, and compositions containing said water soluble compounds | Libragen (FR) | 2010-06-30 | — | — | EP | claimed |
| EP-4069659-B1 | PINOCEMBRIN DIHYDROCHALCONE AND COMPOSITIONS THEREOF AND THEIR USE AS PESTICIDES | METABOLIC INSIGHTS LTD (IL) | 2025-11-05 | — | — | EP | disclosed |
| CN-120887861-A | Acyl phloroglucinol derivative and preparation method and application thereof | 暨南大学 | 2025-11-04 | — | — | CN | disclosed |
| CN-120554325-A | Acyl phloroglucinol derivative and preparation method and application thereof | 暨南大学 | 2025-08-29 | — | — | CN | disclosed |
| US-12382954-B2 | Pinocembrin dihydrochalcone and compositions thereof and their use as pesticides | METABOLIC INSIGHTS LTD. (IL) | 2025-08-12 | — | — | US | disclosed |
| US-20250084049-A1 | POLYCATIONIC SALTS OF PHENOLIC COMPOUNDS AND USES THEREOF | FIRMENICH INCORPORATED (US) | 2025-03-13 | — | — | US | disclosed |
| CN-118805781-A | Pinocembrin dihydrochalcone and compositions thereof and their use as pesticides | 代谢洞察有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-114829320-B | Pinocembrin dihydrochalcone and compositions thereof and their use as pesticides | 代谢洞察有限公司 | 2024-07-19 | — | — | CN | disclosed |
| US-20130177515-A1 | MONOTERPENE DERIVATIVES OF CHALCONE OR DIHYDROCHALCONE AND THEIR USE AS DEPIGMENTING AGENTS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-07-11 | — | — | US | disclosed |
| US-20130177515-A1 | MONOTERPENE DERIVATIVES OF CHALCONE OR DIHYDROCHALCONE AND THEIR USE AS DEPIGMENTING AGENTS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-07-11 | — | — | US | disclosed |
| WO-2012033846-A1 | ARYLPROPIONYL-TRIKETONE ANTIBACTERIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-03-15 | — | — | WO | disclosed |
| EP-2379576-A1 | HYDROSOLUBLE [6)-O-alpha-D-GLCP-(1->]n-6-O-beta-D-GLCP-(1->-PHENOLIC DERIVATIVES WITH DERMOCOSMETIC, NUTRITIONAL AND THERAPEUTIC APPLICATIONS, AND COMPOSITIONS CONTAINING SAID WATER SOLUBLE COMPOUNDS | Libragen (FR) | 2011-10-26 | — | — | EP | disclosed |
| US-20110256115-A1 | HYDROSOLUBLE [6)O-ALPHA-D-GLCP-(1->]N-6-O-BETA-D-GLCP-(1->-PHENOLIC DERIVATIVES WITH DERMOCOSMETIC, NUTRITIONAL AND THERAPEUTIC APPLICATIONS, AND COMPOSITIONS CONTAINING SAID WATER SOLUBLE COMPOUNDS | LIBRAGEN (FR) | 2011-10-20 | — | — | US | disclosed |
| WO-2010072754-A1 | HYDROSOLUBLE [6)O-α-D-GLCP-(1→]n-6-O-β-D-GLCP-(1→-PHENOLIC DERIVATIVES WITH DERMOCOSMETIC, NUTRITIONAL AND THERAPEUTIC APPLICATIONS, AND COMPOSITIONS CONTAINING SAID WATER SOLUBLE COMPOUNDS | LIBRAGEN (FR) | 2010-07-01 | — | — | WO | disclosed |
| EP-2202237-A1 | Hydrosoluble [6)-O-alpha-d-glcp-(1->]n-6-o-bêta-d-glcp-(1->-phenllic derivatives with dermocosmetic, nutritional and therapeutic applications, and compositions containing said water soluble compounds | Libragen (FR) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110256115-A1 | HYDROSOLUBLE [6)O-ALPHA-D-GLCP-(1->]N-6-O-BETA-D-GLCP-(1->-PHENOLIC DERIVATIVES WITH DERMOCOSMETIC, NUTRITIONAL AND THERAPEUTIC APPLICATIONS, AND COMPOSITIONS CONTAINING SAID WATER SOLUBLE COMPOUNDS | UGGT1, UGDH, CYP24A1 | SLC5A1 240/4885SLC5A2 441/4885GAA 9/4885 |
| US-20250084049-A1 | POLYCATIONIC SALTS OF PHENOLIC COMPOUNDS AND USES THEREOF | PGC, SLC5A6, PUF60 | SLC5A1 207/4885SLC5A2 70/4885GAA 544/4885 |
| US-20130177515-A1 | MONOTERPENE DERIVATIVES OF CHALCONE OR DIHYDROCHALCONE AND THEIR USE AS DEPIGMENTING AGENTS | CYP51A1, CDC42, MAP2 | SLC5A1 4754/4885SLC5A2 4714/4885GAA 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.