Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRND | Q07001 | 6/20 | 0.55 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.55 |
| ▸ | CHRNG | P07510 | 2/20 | 0.55 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.55 |
| ▸ | GRIA1 | P42261 | 8/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455132 | 1.00 | CHRND (0.55) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL8964436 | 0.82 | ALDH1A1 (0.49) | — | |
| SCHEMBL10543878 | 0.82 | GRIA1 (0.71) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL10543883 | 0.82 | GRIA1 (0.71) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL453543 | 0.81 | CA2 (0.60) | — | |
| SCHEMBL453542 | 0.81 | CA2 (0.60) | — | |
| SCHEMBL11778440 | 0.80 | CHRND (0.57) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL11796137 | 0.78 | GRIA1 (0.75) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL12527096 | 0.76 | CHRND (0.70) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL5506840 | 0.76 | PKM (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616169-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | Natrix Separations Inc. (CA) | 2013-07-24 | — | — | EP | claimed |
| WO-2012037101-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | NATRIX SEPARATIONS INC. (CA) | 2012-03-22 | — | — | WO | claimed |
| US-20120064601-A1 | Chromatography Membranes for the Purification of Chiral Compounds | NATRIX SEPARATIONS INC. (CA) | 2012-03-15 | — | — | US | claimed |
| EP-2616169-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | Natrix Separations Inc. (CA) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012037101-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | NATRIX SEPARATIONS INC. (CA) | 2012-03-22 | — | — | WO | disclosed |
| US-20120064601-A1 | Chromatography Membranes for the Purification of Chiral Compounds | NATRIX SEPARATIONS INC. (CA) | 2012-03-15 | — | — | US | disclosed |