SCHEMBL45539

SCHEMBL45539

C=C(O)C(=O)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 8/20 0.68
CES1 P23141 7/20 0.68
MAPT P10636 5/20 0.58
LMNA P02545 3/20 0.58
NPSR1 Q6W5P4 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
XBP1 P17861 1/20 0.58
ATM Q13315 1/20 0.58
ALDH1A1 P00352 4/20 0.54
POLB P06746 2/20 0.54
USP2 O75604 1/20 0.54
MAPK1 P28482 1/20 0.54
HTT P42858 1/20 0.54
TSHR P16473 2/20 0.52
DAO P14920 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
EGFR P00533 2/20 0.52
AKT1 P31749 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
CYP3A4 P08684 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28645616 0.91 ALDH1A1 (0.64) CES2CES1MAPTLMNANPSR1
Methoxymethane SCHEMBL27562009 0.91 CES2 (0.56) CES2CES1MAPTLMNANPSR1
Benzil SCHEMBL27564092 0.86 CES2 (0.74) CES2CES1MAPTLMNANPSR1
SCHEMBL4826427 0.83 CES2 (0.68) CES2CES1MAPTLMNANPSR1
Benzil SCHEMBL28225310 0.82 CES2 (0.88) CES2CES1MAPTLMNANPSR1
Benzil SCHEMBL8382614 0.82 CES2 (0.88) CES2CES1MAPTLMNANPSR1
Benzil SCHEMBL9517636 0.82 CES2 (1.00) CES2CES1MAPTLMNASMN1; SMN2
Benzil SCHEMBL7142843 0.82 CES2 (1.00) CES2CES1MAPTLMNASMN1; SMN2
Benzil SCHEMBL66 0.82 CES2 (1.00) CES2CES1MAPTLMNASMN1; SMN2
Benzil SCHEMBL2156589 0.82 CES2 (1.00) CES2CES1MAPTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 297 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240094201-A1 URCHIN-LIKE BEADS WITH ENHANCED OPTICAL PROPERTIES AND METHOD OF MAKING THEREOF ALIGNEDBIO AB (SE) 2024-03-21 US claimed
EP-3774360-B1 UV-CURABLE COMPOSITIONS COMPRISING CLEAVAGE TYPE PHOTOINITIATORS SUN CHEMICAL CORP (US) 2024-01-10 EP claimed
EP-3612577-B1 ELASTOMERIC LATICES AND COATING COMPOSITIONS CONTAINING THE SAME CONSORCIO COMEX S A DE C V (MX) 2024-01-10 EP claimed
US-11359102-B2 UV-curable compositions comprising cleavage type photoinitiators SUN CHEMICAL CORPORATION (US) 2022-06-14 US claimed
US-20210301157-A1 UV-CURABLE COMPOSITIONS COMPRISING CLEAVAGE TYPE PHOTOINITIATORS SUN CHEMICAL CORPORATION (US) 2021-09-30 US claimed
EP-3494151-A1 POLYMERIC DEVICES AND METHODS OF MAKING Microoptx Inc. (US) 2019-06-12 EP claimed
EP-2850111-B1 NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS COLOPLAST AS (DK) 2018-11-21 EP claimed
EP-2850112-B1 NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS COLOPLAST AS (DK) 2018-11-21 EP claimed
US-10040902-B2 Polymeric photoinitiators COLOPLAST A/S (DK) 2018-08-07 US claimed
US-10040893-B2 Polymeric photoinitiators and photoinitiator monomers COLOPLAST A/S (DK) 2018-08-07 US claimed
WO-2012062333-A1 NOVEL POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2012-05-18 WO claimed
WO-2011160637-A2 POLYURETHANE BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO claimed
WO-2011160641-A2 HYDROPHILIC GELS FROM POLYURETHANE-BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO claimed
WO-2011160636-A2 GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO claimed
WO-2011160640-A2 HYDROPHILIC GELS DERIVED FROM GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO claimed
US-5683741-A MIXING PROTON AFFINITIVE INDICATOR WITH RADIATION CURABLE PRINTING INK SO THAT DEGREE OF CROSSLINKING CAN BE MEASURED BY ION MOBILITY SPECTROSCOPY OF GASES WHICH EVAPORATE FROM PRINTED SURFACE AFTER CURING DRUCKFARBENFABRIK GEBR.SCHMIDT GMBH (DE) 1997-11-04 US claimed
US-4971887-A Positive-working photosensitive mixture and recording material of high thermal stability with phenolic novolak of m-cresol and 2,3,6-trialkylphenol HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-20 US claimed
EP-0085024-B1 METHOD FOR PRODUCING IMAGES IN PHOTORESIST LAYERS CIBA-GEIGY AG (CH) 1987-07-15 EP claimed
EP-0036075-B1 MIXTURES BASED ON AROMATIC-ALIPHATIC KETONES, THEIR USE AS PHOTOINITIATORS AND PHOTOPOLYMERISABLE SYSTEMS CONTAINING SUCH MIXTURES MERCK PATENT GmbH (DE) 1984-06-06 EP claimed
US-4439517-A Process for the formation of images with epoxide resin CIBA-GEIGY CORPORATION (US) 1984-03-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10040893-B2 Polymeric photoinitiators and photoinitiator monomers ACMSD, AAAS, PPOX CES2 1721/4885CES1 2461/4885MAPT 91/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.