Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 17/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4554891 | 0.87 | FFAR1 (0.44) | FFAR1 | |
| SCHEMBL4555465 | 0.85 | LMNA (0.44) | — | |
| SCHEMBL4555438 | 0.85 | MTNR1B (0.38) | FFAR1MTNR1BMTNR1A | |
| SCHEMBL4553186 | 0.83 | FFAR1 (0.44) | FFAR1 | |
| SCHEMBL4554911 | 0.82 | MTNR1B (0.36) | MTNR1BMTNR1A | |
| SCHEMBL3725212 | 0.75 | FFAR1 (0.46) | FFAR1 | |
| Hydrochloric Acid SCHEMBL3725783 | 0.74 | FFAR1 (0.45) | FFAR1 | |
| SCHEMBL3728409 | 0.74 | ESR2 (0.48) | FFAR1 | |
| SCHEMBL3665398 | 0.73 | ROCK2 (0.44) | MTNR1BMTNR1A | |
| SCHEMBL4555464 | 0.73 | LMNA (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125799-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | Smithkline Beecham Corporation (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008104524-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | SMITHKLINE BEECHAM CORPORATION (US) | 2008-09-04 | — | — | WO | disclosed |