Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL963508 | 0.87 | HTT (0.42) | RAB9ASMN1; SMN2ALDH1A1NPC1PHGDH | |
| SCHEMBL962886 | 0.83 | ALDH1A1 (0.49) | RAB9ASMN1; SMN2ALDH1A1NPC1PHGDH | |
| SCHEMBL962885 | 0.83 | ALDH1A1 (0.49) | RAB9ASMN1; SMN2ALDH1A1NPC1PHGDH | |
| SCHEMBL4554402 | 0.80 | GLS (0.37) | RAB9ASMN1; SMN2ALDH1A1NPC1GAA | |
| SCHEMBL4553928 | 0.79 | CA12 (0.35) | RAB9ASMN1; SMN2ALDH1A1NPC1PHGDH | |
| SCHEMBL962780 | 0.72 | PPARG (0.39) | RAB9ASMN1; SMN2ALDH1A1NPC1PHGDH | |
| SCHEMBL962779 | 0.72 | PPARG (0.39) | RAB9ASMN1; SMN2ALDH1A1NPC1PHGDH | |
| Potassium Ion SCHEMBL962180 | 0.72 | ASAH1 (0.35) | RAB9ASMN1; SMN2ALDH1A1NPC1PHGDH | |
| SCHEMBL4554658 | 0.70 | CYP1A2 (0.31) | RAB9ASMN1; SMN2ALDH1A1NPC1HPGD | |
| SCHEMBL4554436 | 0.69 | MAPT (0.42) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118066-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | Takeda Pharmaceutical Company Limited (JP) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008099794-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-08-21 | — | — | WO | disclosed |