Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555154 | 0.81 | GPR119 (0.39) | L3MBTL3L3MBTL1 | |
| SCHEMBL4555173 | 0.74 | L3MBTL3 (0.35) | L3MBTL3L3MBTL1 | |
| SCHEMBL4555483 | 0.70 | L3MBTL3 (0.36) | L3MBTL3L3MBTL1 | |
| SCHEMBL4555143 | 0.68 | L3MBTL3 (0.32) | L3MBTL3L3MBTL1 | |
| SCHEMBL4555146 | 0.68 | DPP4 (0.32) | L3MBTL3L3MBTL1 | |
| SCHEMBL4554681 | 0.68 | L3MBTL3 (0.32) | L3MBTL3L3MBTL1 | |
| SCHEMBL4555416 | 0.68 | CTSS (0.50) | CTSS | |
| SCHEMBL4555362 | 0.66 | L3MBTL3 (0.43) | L3MBTL3L3MBTL1 | |
| SCHEMBL4554607 | 0.66 | L3MBTL3 (0.38) | L3MBTL3L3MBTL1 | |
| SCHEMBL4554044 | 0.65 | GPR119 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121661-A1 | BIPIPERIDINYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | Merck & Co., Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008085316-A1 | BIPIPERIDINYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 2008-07-17 | — | — | WO | disclosed |