SCHEMBL4556202

SCHEMBL4556202

CC=Cc1cccc(C(=O)O)c1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PD P11413 1/20 0.52
CASP7 P55210 1/20 0.52
CASP6 P55212 1/20 0.52
MMP2 P08253 1/20 0.43
ALDH1A1 P00352 4/20 0.40
ALOX15 P16050 2/20 0.40
MYC P01106 1/20 0.40
KDM4E B2RXH2 3/20 0.39
HSD17B10 Q99714 3/20 0.39
HPGD P15428 2/20 0.39
NAPRT Q6XQN6 2/20 0.38
MAPT P10636 2/20 0.38
POLB P06746 2/20 0.37
CA12 O43570 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA4 P22748 2/20 0.37
CA7 P43166 2/20 0.37
CA9 Q16790 2/20 0.37
MEN1 O00255 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL891695 0.81 ALDH1A1 (0.52) ALDH1A1ALOX15KDM4EHSD17B10HPGD
SCHEMBL357341 0.81 ALDH1A1 (0.52) ALDH1A1ALOX15KDM4EHSD17B10HPGD
SCHEMBL728576 0.81 ALDH1A1 (0.52) ALDH1A1ALOX15KDM4EHSD17B10HPGD
SCHEMBL27104316 0.80 ALDH1A1 (0.41) G6PDCASP7CASP6MMP2ALDH1A1
SCHEMBL11130587 0.80 ALDH1A1 (0.53) G6PDCASP7CASP6MMP2ALDH1A1
SCHEMBL11130591 0.80 ALDH1A1 (0.53) G6PDCASP7CASP6MMP2ALDH1A1
SCHEMBL25273832 0.79 G6PD (0.57) G6PDCASP7CASP6MMP2ALDH1A1
SCHEMBL7160570 0.79 ALDH1A1 (0.40) G6PDCASP7CASP6ALDH1A1ALOX15
SCHEMBL1536427 0.79 ALB (0.43) G6PDCASP7CASP6ALDH1A1ALOX15
SCHEMBL7160568 0.79 ALDH1A1 (0.40) G6PDCASP7CASP6ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11905231-B1 Solid forms, salts and polymorphs of anti-fibrotic compounds CERTA THERAPEUTICS PTY LTD (AU) 2024-02-20 US disclosed
EP-2035369-A1 THERAPEUTIC COMPOUNDS Fibrotech Therapeutics PTY LTD (AU) 2009-03-18 EP disclosed
WO-2008003141-A1 THERAPEUTIC COMPOUNDS FIBROTECH THERAPEUTICS PTY LTD (AU) 2008-01-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11905231-B1 Solid forms, salts and polymorphs of anti-fibrotic compounds COL2A1, COL1A1, FIBP G6PD 2592/4885CASP7 575/4885CASP6 685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.