Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.34 |
| ▸ | TRDMT1 | O14717 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7050370 | 0.96 | NNMT (0.34) | NNMTCARM1TRDMT1P2RX3P2RX4 | |
| SCHEMBL6895651 | 0.88 | AHCY (0.35) | NNMTCARM1TRDMT1P2RX3P2RX4 | |
| SCHEMBL6898692 | 0.88 | AHCY (0.35) | NNMTCARM1TRDMT1DOT1L | |
| SCHEMBL7914645 | 0.86 | TRDMT1 (0.37) | NNMTCARM1TRDMT1P2RX3P2RX4 | |
| SCHEMBL7920985 | 0.85 | P2RX3 (0.33) | NNMTCARM1TRDMT1P2RX3P2RX4 | |
| SCHEMBL7922845 | 0.85 | CARM1 (0.33) | NNMTCARM1TRDMT1P2RX3P2RX4 | |
| SCHEMBL7254352 | 0.83 | TYMP (0.37) | TYMPADORA1 | |
| SCHEMBL5501797 | 0.83 | CARM1 (0.33) | NNMTCARM1TRDMT1P2RX3P2RX4 | |
| SCHEMBL5403467 | 0.83 | TRDMT1 (0.35) | NNMTCARM1TRDMT1P2RX3P2RX4 | |
| SCHEMBL2109084 | 0.82 | TRDMT1 (0.36) | NNMTCARM1TRDMT1DOT1LTYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090198047-A1 | 2'-Modified Oligonucleotides | ISIS PHARMACEUTICALS, INC. (US) | 2009-08-06 | — | — | US | disclosed |
| US-7138517-B2 | Sugar modified oligonucleotides | ISIS PHARMACEUTICALS, INC. (US) | 2006-11-21 | — | — | US | disclosed |
| US-20030187240-A1 | 2' -modified oligonucleotides | ISIS PHARMACEUTICALS, INC. | 2003-10-02 | — | — | US | disclosed |
| US-20030004325-A1 | Sugar modified oligonucleotides | ISIS PHARMACEUTICALS, INC. | 2003-01-02 | — | — | US | disclosed |
| US-6399754-B1 | CONTAINING SULFOPHOSPHATE GROUP | ISIS PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |