Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRDMT1 | O14717 | 2/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.36 |
| ▸ | NNMT | P40261 | 2/20 | 0.36 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | AHCY | P23526 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15879332 | 0.99 | TRDMT1 (0.36) | TRDMT1CARM1NNMTDOT1LADORA1 | |
| SCHEMBL15048538 | 0.94 | CARM1 (0.34) | TRDMT1CARM1NNMTDOT1LADORA1 | |
| SCHEMBL2213753 | 0.94 | CARM1 (0.34) | TRDMT1CARM1NNMTDOT1LADORA1 | |
| SCHEMBL2108084 | 0.89 | HPGD (0.38) | TYMP | |
| SCHEMBL6895651 | 0.88 | AHCY (0.35) | TRDMT1CARM1NNMTDOT1LAHCY | |
| SCHEMBL2106220 | 0.88 | ADORA1 (0.42) | TRDMT1CARM1NNMTADORA1TYMP | |
| SCHEMBL6898692 | 0.88 | AHCY (0.35) | TRDMT1CARM1NNMTDOT1LAHCY | |
| SCHEMBL1317492 | 0.87 | CARM1 (0.34) | TRDMT1CARM1NNMTDOT1LADORA1 | |
| SCHEMBL15841413 | 0.87 | ADORA1 (0.41) | TRDMT1CARM1NNMTADORA1TYMP | |
| SCHEMBL7914645 | 0.86 | TRDMT1 (0.37) | TRDMT1CARM1NNMTDOT1LADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995253-B1 | METHOD FOR DETACHING PROTECTING GROUP ON NUCLEIC ACID | NIPPON SHINYAKU CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| US-20120322993-A1 | Phosphorylation Reagent | NIPPON SHINYAKU CO., LTD. (JP) | 2012-12-20 | — | — | US | disclosed |
| EP-1795536-B1 | PHOSPHORAMIDITE COMPOUND AND METHOD FOR PRODUCING OLIGO-RNA | NIPPON SHINYAKU CO LTD (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-8158775-B2 | Method for detaching protecting group on nucleic acid | NIPPON SHINYAKU CO., LTD. (JP) | 2012-04-17 | — | — | US | disclosed |
| US-20090312534-A1 | METHOD FOR REMOVAL OF NUCLEIC ACID-PROTECTING GROUP | NIPPON SHINYAKU CO., LTD. (JP) | 2009-12-17 | — | — | US | disclosed |
| US-20090149645-A1 | METHOD FOR DETACHING PROTECTING GROUP ON NUCLEIC ACID | NIPPON SHINYAKU CO., LTD. (JP) | 2009-06-11 | — | — | US | disclosed |
| US-20090137790-A1 | METHOD OF CAPPING OLIGONUCLEIC ACID | NIPPON SHINYAKU CO., LTD. (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-2017282-A1 | METHOD OF CAPPING OLIGONUCLEIC ACID | Nippon Shinyaku Co., Ltd. (JP) | 2009-01-21 | — | — | EP | disclosed |
| EP-1995252-A1 | METHOD FOR REMOVAL OF NUCLEIC ACID-PROTECTING GROUP | Nippon Shinyaku Co., Ltd. (JP) | 2008-11-26 | — | — | EP | disclosed |
| EP-1995253-A1 | METHOD FOR DETACHING PROTECTING GROUP ON NUCLEIC ACID | Nippon Shinyaku Co., Ltd. (JP) | 2008-11-26 | — | — | EP | disclosed |
| US-20070282097-A1 | Phosphoramidite Compound And Method For Producing Oligo-Rna | NIPPON SHINYAKU CO., LTD. (JP) | 2007-12-06 | — | — | US | disclosed |
| EP-1795536-A1 | PHOSPHORAMIDITE COMPOUND AND METHOD FOR PRODUCING OLIGO-RNA | Nippon Shinyaku Co., Ltd. (JP) | 2007-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312534-A1 | METHOD FOR REMOVAL OF NUCLEIC ACID-PROTECTING GROUP | NSUN2, RNASEH1, RNASE1 | TRDMT1 15/4885CARM1 1075/4885NNMT 840/4885 |
| US-20090137790-A1 | METHOD OF CAPPING OLIGONUCLEIC ACID | RNGTT, DUT, ADAR | TRDMT1 33/4885CARM1 1138/4885NNMT 784/4885 |
| US-20070282097-A1 | Phosphoramidite Compound And Method For Producing Oligo-Rna | NSUN2, NSUN3, XRN2 | TRDMT1 47/4885CARM1 1754/4885NNMT 2170/4885 |
| US-20120322993-A1 | Phosphorylation Reagent | CSNK2A2, CSNK2A1, CSNK2B | TRDMT1 3170/4885CARM1 815/4885NNMT 1567/4885 |
| US-20090149645-A1 | METHOD FOR DETACHING PROTECTING GROUP ON NUCLEIC ACID | DNASE1, DNASE1L3, NSUN2 | TRDMT1 29/4885CARM1 349/4885NNMT 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.