Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 4/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5138477 | 0.98 | MAPT (0.51) | MAPTALDH1A1GAAATMLMNA | |
| SCHEMBL11093329 | 0.93 | MAPT (0.49) | MAPTALDH1A1GAAATMLMNA | |
| SCHEMBL6901453 | 0.82 | MAPT (0.61) | MAPTALDH1A1GAAATMLMNA | |
| SCHEMBL27540806 | 0.81 | MAPT (0.53) | MAPTALDH1A1GAAATMLMNA | |
| SCHEMBL9614310 | 0.81 | PGR (0.51) | MAPTALDH1A1GAALMNATSHR | |
| SCHEMBL8769265 | 0.79 | MAPT (0.57) | MAPTALDH1A1GAAATMLMNA | |
| SCHEMBL8570404 | 0.76 | MAPT (0.58) | MAPTALDH1A1GAAATMLMNA | |
| SCHEMBL6545546 | 0.76 | ALDH1A1 (0.61) | MAPTALDH1A1GAAATMLMNA | |
| SCHEMBL1701248 | 0.75 | MAPT (0.53) | MAPTALDH1A1GAAATMLMNA | |
| SCHEMBL10629250 | 0.75 | ALDH1A1 (0.56) | MAPTALDH1A1GAAATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096119-A1 | SALTS 669 | ASTRAZENECA AB (SE) | 2008-08-14 | — | — | WO | claimed |
| CN-1246296-C | Process for preparing 2-ethyl-N-(ethoxy methyl)-alpha-chloroacetanilide | WANG ZHENGQUAN (CN) | 2006-03-22 | — | — | CN | claimed |
| CN-1532183-A | Process for preparing 2-ethyl-N-(ethoxy methyl)-alpha-chloroacetanilide | 王正权 | 2004-09-29 | — | — | CN | claimed |
| EP-2124941-A1 | COMBINATION OF A MUSCARINIC RECEPTOR ANTAGONIST AND A BETA-2-ADRENOCEPTOR AGONIST | Argenta Discovery Limited (GB) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008096126-A1 | COMBINATION OF A MUSCARINIC RECEPTOR ANTAGONIST AND A BETA-2-ADRENOCEPTOR AGONIST | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |
| US-4296254-A | N-METHYLENE ETHER-2-HALOACETAMIDES, ACID CATALYST | MONSANTO COMPANY (US) | 1981-10-20 | — | — | US | disclosed |