Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158241 | 0.88 | SIRT1 (0.42) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL27639755 | 0.84 | PRSS1 (0.44) | IKBKBDHODHJAK2JAK3ERCC5 | |
| Dimethylamine SCHEMBL27576834 | 0.82 | LMNA (0.40) | MAPTSMN1; SMN2LMNAGAATSHR | |
| SCHEMBL27829888 | 0.81 | HDAC1 (0.44) | IKBKBKIF11MAPTMKNK2KDM4E | |
| SCHEMBL28233528 | 0.80 | TRPA1 (0.47) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL27639739 | 0.80 | PARP10 (0.53) | SMN1; SMN2TSHRERCC5FEN1 | |
| SCHEMBL6034931 | 0.79 | MTNR1A (0.42) | NPC1RAB9AMAPTLMNAGAA | |
| SCHEMBL27345974 | 0.79 | CA1 (0.46) | NPC1RAB9AIKBKB | |
| SCHEMBL27967263 | 0.78 | TSHR (0.48) | SMN1; SMN2TSHRHTT | |
| SCHEMBL19345940 | 0.78 | CYP3A4 (0.42) | NPC1RAB9AKIF11MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1849301-A | Substituted arylthiourea derivatives useful as inhibitors of viral replication | ACHILLION PHARMACEUTICALS INC (US) | 2006-10-18 | — | — | CN | claimed |
| EP-0382425-B1 | Optical recording medium | JUJO PAPER CO LTD (JP) | 1994-06-22 | — | — | EP | claimed |
| US-5079304-A | Curable | ZEON CHEMICALS U.S.A., INC. (US) | 1992-01-07 | — | — | US | claimed |
| EP-0083075-B1 | COLOUR DEVELOPING SHEET FOR A PRESSURE-SENSITIVE RECORDING SHEET | JUJO PAPER CO., LTD. (JP) | 1986-08-13 | — | — | EP | claimed |
| EP-2097473-B1 | MASTER BLENDS INCLUDING AN ETHYLENE AND ALPHA-OLEFINE COPOLYMER AS A CARRIER AND CONTAINING VULCANISATION AGENTS | MLPC INTERNAT (FR) | 2015-10-14 | — | — | EP | disclosed |
| EP-2097473-A2 | MASTER BLENDS INCLUDING AN ETHYLENE AND ALPHA-OLEFINE COPOLYMER AS A CARRIER AND CONTAINING VULCANISATION AGENTS | MLPC International (FR) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008074962-A2 | MASTER BLENDS INCLUDING AN ETHYLENE AND ALPHA-OLEFINE COPOLYMER AS A CARRIER AND CONTAINING VULCANISATION AGENTS | MLPC INTERNATIONAL (FR) | 2008-06-26 | — | — | WO | disclosed |
| EP-1275693-B1 | IMPACT MODIFIER, PROCESS FOR PRODUCING THE SAME, AND THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME | MITSUBISHI RAYON CO (JP) | 2006-01-11 | — | — | EP | disclosed |
| US-6833409-B2 | Graft-polymerizing a polyalkyl (meth)acrylate with a vinyl monomer and a compound which has a sulfonic or sulfuric acid group each having a different glass transition temperature | MITSUBISHI RAYON CO., LTD. (JP) | 2004-12-21 | — | — | US | disclosed |
| US-20030114588-A1 | Impact modifier, process for producing the same, and thermoplastic resin composition containing the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-06-19 | — | — | US | disclosed |
| EP-1275693-A1 | IMPACT MODIFIER, PROCESS FOR PRODUCING THE SAME, AND THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME | Mitsubishi Rayon Co., Ltd. (JP) | 2003-01-15 | — | — | EP | disclosed |
| WO-1994025253-A1 | SHORT-FIBER-REINFORCED PLASTIC FOILS | SIKA AG, VORM. KASPAR WINKLER & CO. (CH) | 1994-11-10 | — | — | WO | disclosed |
| US-4082711-A | COELASTOMER, PLASTICIZING | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-04-04 | — | — | US | disclosed |