Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10576223 | 1.00 | ALDH1A1 (0.46) | ALDH1A1GAAHSD17B10KDM4EGLA | |
| SCHEMBL2893747 | 1.00 | ALDH1A1 (0.46) | ALDH1A1GAAHSD17B10KDM4EGLA | |
| SCHEMBL11646457 | 0.78 | CMA1 (0.43) | ALDH1A1GAAHSD17B10KDM4EGLA | |
| SCHEMBL17294177 | 0.74 | HDAC1 (0.46) | ALDH1A1GAAHPGDMAPK1CMA1 | |
| SCHEMBL7104749 | 0.74 | ADAMTS5 (0.46) | ALDH1A1CYP3A4CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL9422803 | 0.74 | ADAMTS5 (0.46) | ALDH1A1CYP3A4CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL102280 | 0.72 | LMNA (0.50) | ALDH1A1GAAHSD17B10KDM4EHPGD | |
| SCHEMBL2893907 | 0.71 | SMN1; SMN2 (0.52) | ALDH1A1KDM4ESMN1; SMN2NPSR1KMT2A | |
| SCHEMBL14248574 | 0.71 | CYP3A4 (0.51) | ALDH1A1GAACMA1CYP3A4SLC6A2 | |
| SCHEMBL11644296 | 0.71 | ALDH1A1 (0.47) | ALDH1A1GAAHSD17B10KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557175-B2 | Poly(carbonate-co-urea) copolymers and melt transesterification method of preparing these copolymers | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-07-07 | — | — | US | disclosed |