Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | RPLP1 | P05386 | 2/20 | 0.36 |
| ▸ | RPLP0 | P05388 | 2/20 | 0.36 |
| ▸ | RPS17 | P08708 | 2/20 | 0.36 |
| ▸ | RPSA | P08865 | 2/20 | 0.36 |
| ▸ | RPS2 | P15880 | 2/20 | 0.36 |
| ▸ | RPL35A | P18077 | 2/20 | 0.36 |
| ▸ | RPL7 | P18124 | 2/20 | 0.36 |
| ▸ | RPL17 | P18621 | 2/20 | 0.36 |
| ▸ | RPS4Y1 | P22090 | 2/20 | 0.36 |
| ▸ | RPS3 | P23396 | 2/20 | 0.36 |
| ▸ | RPS12 | P25398 | 2/20 | 0.36 |
| ▸ | RPL13 | P26373 | 2/20 | 0.36 |
| ▸ | RPL10 | P27635 | 2/20 | 0.36 |
| ▸ | RPL12 | P30050 | 2/20 | 0.36 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 2/20 | 0.36 |
| ▸ | RPL22 | P35268 | 2/20 | 0.36 |
| ▸ | RPL4 | P36578 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457514 | 0.84 | CHRNB2 (0.36) | CNR2CHRNB2CHRNA4DDB1CRBN | |
| SCHEMBL456356 | 0.75 | RAB9A (0.43) | RAB9ACNR2KCNH2RPLP1RPLP0 | |
| SCHEMBL27593728 | 0.72 | CNR2 (0.50) | RAB9ACNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL8986053 | 0.69 | CNR2 (0.48) | RAB9ACNR2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL456347 | 0.68 | FAAH (0.47) | RAB9ACNR2 | |
| SCHEMBL970997 | 0.68 | CNR2 (0.53) | RAB9ACNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL5793101 | 0.68 | CNR2 (0.47) | RAB9ACNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL5793106 | 0.68 | CNR2 (0.47) | RAB9ACNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL7376431 | 0.68 | CNR2 (0.44) | RAB9ACNR2 | |
| SCHEMBL4404077 | 0.68 | CNR2 (0.64) | RAB9ACNR2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2613630-A1 | HYDROGEN BOND FORMING FLUORO KETOLIDES FOR TREATING DISEASES | Cempra Pharmaceuticals, Inc. (US) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012034058-A1 | HYDROGEN BOND FORMING FLUORO KETOLIDES FOR TREATING DISEASES | CEMPRA PHARMACEUTICALS, INC. (US) | 2012-03-15 | — | — | WO | disclosed |