Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ACLY | P53396 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.49 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.48 |
| ▸ | ITGA1 | P56199 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31261221 | 0.81 | ACLY (0.60) | KMT2ALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL23141245 | 0.81 | ACLY (0.60) | KMT2ALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL7572290 | 0.80 | LMNA (0.72) | TSHRKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL4565254 | 0.79 | IKBKB (0.67) | TSHRKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL7588364 | 0.78 | SLC40A1 (0.63) | TSHRKMT2ALMNAHPGDNPC1 | |
| SCHEMBL7589259 | 0.77 | TSHR (0.48) | TSHRKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL397473 | 0.77 | TSHR (0.65) | TSHRKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL4799566 | 0.77 | ALDH1A1 (0.63) | TSHRKMT2ALMNAALDH1A1HPGD | |
| SCHEMBL14574872 | 0.76 | TSHR (0.72) | TSHRKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL2634116 | 0.76 | TSHR (0.84) | TSHRKMT2ALMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |