SCHEMBL456642

SCHEMBL456642

OCc1cc(Cl)ccc1B(O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
HIF1A Q16665 3/20 0.42
MEN1 O00255 2/20 0.42
CYP3A4 P08684 2/20 0.42
HPGD P15428 2/20 0.42
ALOX15 P16050 2/20 0.42
KMT2A Q03164 2/20 0.42
SLC22A1 O15245 1/20 0.42
USP2 O75604 1/20 0.42
LMNA P02545 1/20 0.42
HSP90AA1 P07900 1/20 0.42
HSPD1 P10809 1/20 0.42
HSPA5 P11021 1/20 0.42
IDO1 P14902 1/20 0.42
ALOX12 P18054 1/20 0.42
CASP1 P29466 1/20 0.42
HTT P42858 1/20 0.42
BLM P54132 1/20 0.42
HSPE1 P61604 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31164052 1.00 MAPT (0.42) MAPTHIF1AMEN1CYP3A4HPGD
SCHEMBL12556949 0.83 HIF1A (0.42) MAPTHIF1AMEN1CYP3A4HPGD
SCHEMBL20245771 0.82 FLT1 (0.43) MAPTHIF1AMEN1CYP3A4HPGD
SCHEMBL1828589 0.79 ENPP2 (0.40) MAPTHIF1AMEN1CYP3A4HPGD
SCHEMBL29954309 0.79 ENPP2 (0.40) MAPTHIF1AMEN1CYP3A4HPGD
SCHEMBL16576630 0.79 MEN1 (0.38) MAPTHIF1AMEN1CYP3A4HPGD
SCHEMBL15702937 0.77 MAPT (0.36) MAPTHIF1AMEN1CYP3A4HPGD
SCHEMBL3784877 0.77 ENPP2 (0.45) MAPTENPP2HSD17B10
SCHEMBL17419154 0.77 LIPG (0.39)
SCHEMBL28526616 0.77 TYR (0.38) MAPTMEN1CYP3A4ALOX15KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11495769-B2 Inorganic light emitting diode and inorganic light emitting device including the same LG DISPLAY CO., LTD. (KR) 2022-11-08 US claimed
US-20210167321-A1 INORGANIC LIGHT EMITTING DIODE AND INORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2021-06-03 US claimed
US-20250161266-A1 Antibacterial 4.5 Diaryl-Thiophen-2-YL Hexafluoropropan-2-OLS DENOVAMED INC. (CA) 2025-05-22 US disclosed
EP-4519265-A1 IRREVERSIBLE MUTEGFR INHIBITORS Bayer Aktiengesellschaft (DE) 2025-03-12 EP disclosed
EP-4504714-A1 ANTIBACTERIAL 4,5 DIARYL-THIOPHEN-2-YL HEXAFLUOROPROPAN-2-OLS Denovamed Inc. (CA) 2025-02-12 EP disclosed
WO-2023213882-A1 IRREVERSIBLE MUTEGFR INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 2023-11-09 WO disclosed
WO-2023193101-A1 ANTIBACTERIAL 4,5 DIARYL-THIOPHEN-2-YL HEXAFLUOROPROPAN-2-OLS DENOVAMED INC. (CA) 2023-10-12 WO disclosed
US-11495769-B2 Inorganic light emitting diode and inorganic light emitting device including the same LG DISPLAY CO., LTD. (KR) 2022-11-08 US disclosed
US-20210167321-A1 INORGANIC LIGHT EMITTING DIODE AND INORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2021-06-03 US disclosed
US-9776995-B2 Bicyclic sulfonamide compounds as sodium channel inhibitors AMGEN INC. (US) 2017-10-03 US disclosed
US-20160137636-A1 Bicyclic Sulfonamide Compounds as Sodium Channel Inhibitors AMGEN INC. 2016-05-19 US disclosed
US-9255100-B2 Substituted imidazopyridazines BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-02-09 US disclosed
EP-2614063-B1 SUBSTITUTED IMIDAZOPYRIDAZINES BAYER IP GMBH (DE) 2016-01-13 EP disclosed
WO-2014201173-A1 BICYCLIC SULFONAMIDE COMPOUNDS AS SODIUM CHANNEL INHIBITORS AMGEN INC. (US) 2014-12-18 WO disclosed
US-20130338133-A1 SUBSTITUTED IMIDAZOPYRIDAZINES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-12-19 US disclosed
EP-2614063-A1 SUBSTITUTED IMIDAZOPYRIDAZINES Bayer Intellectual Property GmbH (DE) 2013-07-17 EP disclosed
WO-2012032031-A1 SUBSTITUTED IMIDAZOPYRIDAZINES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2012-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130338133-A1 SUBSTITUTED IMIDAZOPYRIDAZINES BUB1, TTBK1, BUB1B MAPT 948/4885HIF1A 1747/4885MEN1 864/4885
US-20250161266-A1 Antibacterial 4.5 Diaryl-Thiophen-2-YL Hexafluoropropan-2-OLS MRPL21, TLR6, TLL2 MAPT 4766/4885HIF1A 4230/4885MEN1 3198/4885
US-20160137636-A1 Bicyclic Sulfonamide Compounds as Sodium Channel Inhibitors SCN7A, SCN1A, SCN5A MAPT 3282/4885HIF1A 2451/4885MEN1 4365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.