SCHEMBL3784877

SCHEMBL3784877

OCc1ccc(B(O)O)c(CO)c1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.45
HSD17B10 Q99714 1/20 0.38
LIPG Q9Y5X9 7/20 0.38
LPL P06858 6/20 0.38
EGFR P00533 1/20 0.37
KDM4E B2RXH2 1/20 0.36
CASP6 P55212 1/20 0.36
MAPT P10636 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
SHBG P04278 1/20 0.35
PKM P14618 1/20 0.33
TRPV1 Q8NER1 1/20 0.33
MGLL Q99685 1/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30632096 0.88 ENPP2 (0.42) ENPP2HSD17B10LIPGLPLEGFR
SCHEMBL3791071 0.83 ENPP2 (0.45) ENPP2HSD17B10LIPGLPLEGFR
SCHEMBL28526616 0.78 TYR (0.38) ENPP2LIPGEGFRMAPTPKM
SCHEMBL17419154 0.78 LIPG (0.39) LIPGLPLCA2
SCHEMBL29653353 0.78 ENPP2 (0.45) ENPP2HSD17B10LIPGLPLSHBG
SCHEMBL6487851 0.78 ENPP2 (0.45) ENPP2HSD17B10LIPGLPLSHBG
SCHEMBL31164052 0.77 MAPT (0.42) ENPP2HSD17B10MAPT
SCHEMBL3790270 0.77 PRKCI (0.40) ENPP2LIPGKDM4EMAPT
SCHEMBL456642 0.77 MAPT (0.42) ENPP2HSD17B10MAPT
SCHEMBL2295096 0.77 ENPP2 (0.44) ENPP2HSD17B10LIPGLPLCYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9085590-B2 Protecting groups for boronic acids WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-07-21 US disclosed
WO-2014153041-A1 PROTECTING GROUPS FOR BORONIC ACIDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2014-09-25 WO disclosed
US-20140275601-A1 PROTECTING GROUPS FOR BORONIC ACIDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2014-09-18 US disclosed
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 ENPP2 1920/4885HSD17B10 1100/4885LIPG 3010/4885
US-20140275601-A1 PROTECTING GROUPS FOR BORONIC ACIDS BRS3, CD79B, NR0B2 ENPP2 3403/4885HSD17B10 1280/4885LIPG 3340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.