⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15638350 | 0.80 | ALDH1A1 (0.39) | — | |
| SCHEMBL8129071 | 0.72 | KEAP1 (0.40) | — | |
| SCHEMBL2972 | 0.72 | — | — | |
| SCHEMBL5584043 | 0.72 | LMNA (0.31) | — | |
| SCHEMBL59224 | 0.72 | — | — | |
| SCHEMBL2884608 | 0.72 | ACHE (0.42) | — | |
| SCHEMBL7818368 | 0.69 | RAB9A (0.38) | — | |
| SCHEMBL10927467 | 0.69 | CA2 (0.39) | — | |
| SCHEMBL2972382 | 0.69 | MAPT (0.38) | — | |
| SCHEMBL2972829 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891466-A | Pyrazole-containing dithiazole carboxamide derivative and preparation method and application thereof | 南开大学 | 2023-10-17 | — | — | CN | claimed |
| CN-114213353-A | Aryl-oxazole-oxazoline compound and preparation method and application thereof | 贵州大学 | 2022-03-22 | — | — | CN | claimed |
| CN-102746297-B | Oxazolidinone antibiotics | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-08-26 | — | — | CN | claimed |
| EP-2903440-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | Bayer CropScience AG (DE) | 2015-08-12 | — | — | EP | claimed |
| CN-102459166-B | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA NV | 2015-03-25 | — | — | CN | claimed |
| WO-2014053450-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-04-10 | — | — | WO | claimed |
| US-8507473-B2 | 3H-imidazo[4,5-b]pyridin-5-ol derivatives useful in the treatment of GPR81 receptor disorders | ARENA PHARMACEUTICALS, INC. (US) | 2013-08-13 | — | — | US | claimed |
| US-20110172209-A1 | 3H-IMIDAZO[4,5-B]PYRIDIN-5-OL DERIVATIVES USEFUL IN THE TREATMENT OF GPR81 RECEPTOR DISORDERS | ARENA PHARMACEUTICALS, INC. (US) | 2011-07-14 | — | — | US | claimed |
| WO-2010030360-A1 | 3H-IMIDAZO[4,5-b]PYRIDIN-5-OL DERIVATIVES USEFUL IN THE TREATMENT OF GPR81 RECEPTOR DISORDERS | ARENA PHARMACEUTICALS, INC. (US) | 2010-03-18 | — | — | WO | claimed |
| WO-2006114402-A1 | SUBSTITUTED OCTAHYDROISOINDOLES AS ANTAGONISTS OF MELANIN CONCENTRATING HORMONE RECEPTOR 1 (MCH1R) | BIOVITRUM AB (PUBL) (SE) | 2006-11-02 | — | — | WO | claimed |
| US-5700831-A | INSECTICIDE, NEMATOCIDES, MITICIDES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1997-12-23 | — | — | US | claimed |
| WO-1997033862-A1 | PESTICIDAL HYDRAZIDE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1997-09-18 | — | — | WO | claimed |
| EP-0492839-B1 | Selective acylation of hydrazines | ROHM & HAAS (US) | 1995-04-12 | — | — | EP | claimed |
| EP-0492839-A1 | Selective acylation of hydrazines | ROHM AND HAAS COMPANY (US) | 1992-07-01 | — | — | EP | claimed |
| US-4551464-A | AND SULFIMINO CARBOSTYRILS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-11-05 | — | — | US | claimed |
| EP-0071150-B1 | SULFIMINES, THEIR SALTS AND THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1985-07-03 | — | — | EP | claimed |
| US-4442111-A | Antithrombotic sulfimino and sulfoximino indolinones-2 | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-04-10 | — | — | US | claimed |
| EP-0071150-A1 | Sulfimines, their salts and their preparation, and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1983-02-09 | — | — | EP | claimed |
| CN-116891466-A | Pyrazole-containing dithiazole carboxamide derivative and preparation method and application thereof | 南开大学 | 2023-10-17 | — | — | CN | disclosed |
| US-3960873-A | 1-Phenylthiopropyl-4-hydroxy-4-phenyl piperidines | SUMITOMO CHEMICAL CO., LTD. (JA) | 1976-06-01 | — | — | US | disclosed |