Sugi Predict

Sugi Predict / Compounds / SCHEMBL4569159

SCHEMBL4569159

SCHEMBL4569159

CC(C)(C)OC(=O)NCCOCc1cccc(OCC2CCCCC2)c1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ACACB O00763 2/20 0.44
▸ ACACA Q13085 2/20 0.44
▸ CACNA1B Q00975 1/20 0.43
▸ SLC2A1 P11166 1/20 0.42
▸ KAT6A Q92794 1/20 0.42
▸ SIRT2 Q8IXJ6 1/20 0.41
▸ FFAR1 O14842 2/20 0.41
▸ PPARD Q03181 2/20 0.41
▸ ADAM17 P78536 1/20 0.41
▸ BCHE P06276 1/20 0.41
▸ CNR2 P34972 1/20 0.41
▸ IDO1 P14902 1/20 0.41
▸ EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23115243 0.87 ACACB (0.47) ACACBACACASLC2A1SIRT2
SCHEMBL4569164 0.82 SLC2A1 (0.44) ACACBACACACACNA1BSLC2A1KAT6A
SCHEMBL29818794 0.81 SLC2A1 (0.43) ACACBACACACACNA1BSLC2A1KAT6A
SCHEMBL4569166 0.81 SLC2A1 (0.43) ACACBACACACACNA1BSLC2A1KAT6A
SCHEMBL30029020 0.81 MTNR1A (0.47) ACACBACACAKAT6ASIRT2ADAM17
SCHEMBL25819794 0.81 HTR2C (0.45) ACACBACACASLC2A1KAT6ASIRT2
SCHEMBL2202457 0.80 KAT6A (0.46) ACACBACACASLC2A1KAT6ASIRT2
SCHEMBL2205062 0.80 KAT6A (0.47) ACACBACACASLC2A1KAT6ASIRT2
SCHEMBL4569040 0.80 KAT6A (0.47) ACACBACACASLC2A1KAT6ASIRT2
SCHEMBL2207739 0.80 CETP (0.43) ACACBACACACACNA1BSLC2A1KAT6A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230218549-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2023-07-13 — — US disclosed
US-20210077427-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2021-03-18 — — US disclosed
US-10639286-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2020-05-05 — — US disclosed
US-20190183816-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2019-06-20 — — US disclosed
US-10188615-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2019-01-29 — — US disclosed
US-20180177746-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2018-06-28 — — US disclosed
US-20180177746-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2018-06-28 — — US disclosed
EP-3210966-A1 ALKOXYPHENYLPROPYLAMINES FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION Acucela, Inc. (US) 2017-08-30 — — EP disclosed
US-9737496-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2017-08-22 — — US disclosed
US-9737496-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2017-08-22 — — US disclosed
US-8829244-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2014-09-09 — — US disclosed
US-8829244-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2014-09-09 — — US disclosed
US-20130197096-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA, INC. (US) 2013-08-01 — — US disclosed
US-20130197096-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA, INC. (US) 2013-08-01 — — US disclosed
US-20120214852-A1 Alkoxy Compounds for Disease Treatment ACUCELA INC. (US) 2012-08-23 — — US disclosed
US-20120129894-A1 Alkoxy Compounds for Disease Treatment ACUCELA INC. (US) 2012-05-24 — — US disclosed
US-20120122938-A1 Alkoxy Compounds for Disease Treatment ACUCELA INC. (US) 2012-05-17 — — US disclosed
US-7982071-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2011-07-19 — — US disclosed
US-20090326074-A1 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2009-12-31 — — US disclosed
WO-2009045479-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. (US) 2009-04-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120122938-A1 Alkoxy Compounds for Disease Treatment ALDH1A2, CLN6, AGER ACACB 139/4885ACACA 229/4885CACNA1B 4265/4885
US-20210077427-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER ACACB 139/4885ACACA 229/4885CACNA1B 4265/4885
US-20230218549-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER ACACB 142/4885ACACA 236/4885CACNA1B 4210/4885
US-20190183816-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER ACACB 139/4885ACACA 229/4885CACNA1B 4265/4885
US-20130197096-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER ACACB 139/4885ACACA 229/4885CACNA1B 4265/4885
US-20120214852-A1 Alkoxy Compounds for Disease Treatment ALDH1A2, CLN6, AGER ACACB 139/4885ACACA 229/4885CACNA1B 4265/4885
US-20090326074-A1 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER ACACB 139/4885ACACA 229/4885CACNA1B 4265/4885
US-10188615-B2 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER ACACB 139/4885ACACA 229/4885CACNA1B 4265/4885
US-20180177746-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER ACACB 139/4885ACACA 229/4885CACNA1B 4265/4885
US-20120129894-A1 Alkoxy Compounds for Disease Treatment ALDH1A2, CLN6, AGER ACACB 139/4885ACACA 229/4885CACNA1B 4265/4885
US-10639286-B2 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER ACACB 139/4885ACACA 229/4885CACNA1B 4265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.