Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 5/20 | 0.41 |
| ▸ | DHODH | Q02127 | 4/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457066 | 0.79 | KDM4E (0.40) | KDM4ENPC1POLBRAB9AATM | |
| SCHEMBL455865 | 0.77 | SMN1; SMN2 (0.46) | KDM4ENPC1RAB9AATMLMNA | |
| SCHEMBL456840 | 0.77 | IKBKB (0.43) | KDM4EPOLBNOTUMGFERMKNK1 | |
| SCHEMBL3051778 | 0.67 | NPC1 (0.61) | KDM4ENPC1POLBRAB9AATM | |
| SCHEMBL1041002 | 0.67 | HDAC3 (0.55) | KDM4ENPC1POLBRAB9AATM | |
| SCHEMBL1435664 | 0.67 | GFER (0.45) | KDM4ENPC1POLBRAB9AATM | |
| SCHEMBL3055345 | 0.67 | TNIK (0.52) | KDM4ENPC1POLBRAB9AATM | |
| SCHEMBL6203307 | 0.66 | DHODH (0.43) | KDM4ENPC1POLBRAB9AATM | |
| SCHEMBL1559080 | 0.65 | — | — | |
| SCHEMBL197238 | 0.65 | KIF11 (0.78) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |