Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276200 | 0.93 | CES2 (0.53) | NPSR1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL275645 | 0.93 | CES2 (0.53) | NPSR1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL18961632 | 0.91 | CES2 (0.51) | NPSR1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL18972880 | 0.81 | CYP19A1 (0.50) | NPSR1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL18961675 | 0.81 | CYP19A1 (0.50) | NPSR1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL1837474 | 0.81 | CA1 (0.50) | NPSR1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL1837473 | 0.81 | CA1 (0.50) | NPSR1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL18961674 | 0.80 | CES2 (0.44) | NPSR1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL18961644 | 0.78 | CYP19A1 (0.47) | NPSR1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL2957320 | 0.78 | ALDH1A1 (0.70) | NPSR1MAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765156-B2 | Topical compositions comprising inorganic particulates and an alkoxylated diphenylacrylate compound | ELC MANAGEMENT LLC (US) | 2014-07-01 | — | — | US | disclosed |
| US-20120201766-A1 | Topical Compositions Comprising An Alkoxylated Diphenylacrylate Compound And An Organic Nonionic Emulsifier | ELC MANAGEMENT LLC | 2012-08-09 | — | — | US | disclosed |
| US-20120134943-A1 | Topical Compositions Comprising An Alkoxylated Diphenylacrylate Compound And An Aryl Carboxylic Ester | ELC MANAGEMENT LLC | 2012-05-31 | — | — | US | disclosed |
| US-20120121673-A1 | Topical Compositions Comprising Inorganic Particulates And An Alkoxylated Diphenylacrylate Compound | SUSAK MILANKA (CA) | 2012-05-17 | — | — | US | disclosed |
| US-20110110988-A1 | Topical Compositions Comprising Inorganic Particulates And An Alkoxylated Diphenylacrylate Compound | ELC MANAGEMENT LLC | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120201766-A1 | Topical Compositions Comprising An Alkoxylated Diphenylacrylate Compound And An Organic Nonionic Emulsifier | CUTA, ALAD, DSG1 | NPSR1 4757/4885MAPT 143/4885ALDH1A1 39/4885 |
| US-20110110988-A1 | Topical Compositions Comprising Inorganic Particulates And An Alkoxylated Diphenylacrylate Compound | CUTA, ALAD, AAAS | NPSR1 4674/4885MAPT 131/4885ALDH1A1 53/4885 |
| US-20120121673-A1 | Topical Compositions Comprising Inorganic Particulates And An Alkoxylated Diphenylacrylate Compound | CUTA, ALAD, AAAS | NPSR1 4674/4885MAPT 131/4885ALDH1A1 53/4885 |
| US-20120134943-A1 | Topical Compositions Comprising An Alkoxylated Diphenylacrylate Compound And An Aryl Carboxylic Ester | CUTA, TYR, ACMSD | NPSR1 4872/4885MAPT 101/4885ALDH1A1 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.