SCHEMBL4570805

SCHEMBL4570805

Brc1ccc(-c2ccc3oc4ccccc4c3c2)c2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.47
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 3/20 0.47
HPGD P15428 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
NPC1 O15118 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
RAB9A P51151 1/20 0.47
AHR P35869 2/20 0.43
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
ALOX5 P09917 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
TNKS O95271 1/20 0.40
PLA2G2A P14555 3/20 0.38
PLA2G4A P47712 3/20 0.38
IDO1 P14902 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18271575 0.85 AHR (0.41) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL3046955 0.85 MAPT (0.49) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL30513484 0.85 MAPT (0.49) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL26750757 0.84 HPGD (0.52) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL22376992 0.83 ALOX5 (0.46) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL21283017 0.82 MAPT (0.57) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL18731994 0.81 AHR (0.54) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL18732009 0.81 AHR (0.54) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL16801079 0.81 MAPT (0.49) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL21430424 0.81 PLA2G2A (0.46) MAPTKDM4EALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022729-B2 Compound for organic electric element, organic electric element comprising the same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2024-06-25 US disclosed
US-12022729-B2 Compound for organic electric element, organic electric element comprising the same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2024-06-25 US disclosed
EP-3754737-B1 ORGANIC COMPOUND FOR ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DIODE INCLUDING SAME SFC CO LTD (KR) 2023-08-16 EP disclosed
US-20200403165-A1 ORGANIC COMPOUND FOR ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DIODE INCLUDING SAME SFC CO., LTD. (KR) 2020-12-24 US disclosed
EP-3754737-A1 ORGANIC COMPOUND FOR ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DIODE INCLUDING SAME SFC Co., Ltd. (KR) 2020-12-23 EP disclosed
US-20180226585-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC APPARATUS THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-08-09 US disclosed
US-20120112179-A1 FLUORANTHENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20120112179-A1 FLUORANTHENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12022729-B2 Compound for organic electric element, organic electric element comprising the same, and electronic device thereof PIEZO1, VDAC2, ORAI2 MAPT 616/4885KDM4E 440/4885ALDH1A1 1855/4885
US-20120112179-A1 FLUORANTHENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME AFF1, TCF12, AFF2 MAPT 3978/4885KDM4E 3677/4885ALDH1A1 772/4885
US-20180226585-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC APPARATUS THEREOF PIEZO1, ORAI2, VDAC2 MAPT 1079/4885KDM4E 518/4885ALDH1A1 1529/4885
US-20200403165-A1 ORGANIC COMPOUND FOR ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DIODE INCLUDING SAME CHRM1, ORMDL3, MAP1LC3B MAPT 365/4885KDM4E 2981/4885ALDH1A1 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.