Sugi Predict

Sugi Predict / Compounds / SCHEMBL4572038

SCHEMBL4572038

SCHEMBL4572038

Cc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FTO Q9C0B1 10/20 0.72
▸ MAPT P10636 4/20 0.72
▸ MEN1 O00255 3/20 0.72
▸ KMT2A Q03164 3/20 0.72
▸ HPGD P15428 2/20 0.72
▸ HTT P42858 2/20 0.72
▸ TDP1 Q9NUW8 2/20 0.72
▸ CYP2C19 P33261 1/20 0.72
▸ RECQL P46063 1/20 0.72
▸ BLM P54132 1/20 0.72
▸ SMAD3 P84022 1/20 0.72
▸ PRMT1 Q99873 1/20 0.72
▸ ACE2 Q9BYF1 1/20 0.72
▸ LMNA P02545 4/20 0.57
▸ ALOX12 P18054 2/20 0.57
▸ NPSR1 Q6W5P4 2/20 0.57
▸ GPR55 Q9Y2T6 2/20 0.57
▸ POLB P06746 1/20 0.57
▸ ALDH1A1 P00352 3/20 0.51
▸ ALOX15 P16050 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12863674 0.91 FTO (0.85) FTOMAPTMEN1KMT2AHPGD
SCHEMBL16666150 0.91 FTO (0.60) FTOMAPTMEN1KMT2AHPGD
SCHEMBL6666215 0.90 FTO (0.71) FTOMAPTMEN1KMT2AHPGD
SCHEMBL15496804 0.90 FTO (0.86) FTOMAPTMEN1KMT2AHPGD
SCHEMBL27833470 0.90 FTO (0.83) FTOMAPTMEN1KMT2AHPGD
SCHEMBL26417799 0.88 FTO (0.60) FTOMAPTMEN1KMT2AHPGD
SCHEMBL8265613 0.88 FTO (0.60) FTOMAPTMEN1KMT2AHPGD
SCHEMBL20438522 0.88 FTO (0.60) FTOMAPTMEN1KMT2AHPGD
SCHEMBL17035192 0.88 FTO (0.60) FTOMAPTMEN1KMT2AHPGD
SCHEMBL7600556 0.87 FTO (0.56) FTOMAPTMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3665161-B1 NEW TARGETED CYTOTOXIC RATJADONE DERIVATIVES AND CONJUGATES THEREOF HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) 2023-09-27 — — EP disclosed
US-20230286931-A1 NOVEL BENZOXAZOLE DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF TO DETECT GHB IN DRINKS AND URINE UNIVERSITAT DE VALÈNCIA (ES) 2023-09-14 — — US disclosed
US-20230286931-A1 NOVEL BENZOXAZOLE DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF TO DETECT GHB IN DRINKS AND URINE UNIVERSITAT DE VALÈNCIA (ES) 2023-09-14 — — US disclosed
EP-4194444-A1 NOVEL BENZOXAZOLE DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF TO DETECT GHB IN DRINKS AND URINE Universitat de València (ES) 2023-06-14 — — EP disclosed
EP-3562823-B1 FUNCTIONALIZED NANOLUC INHIBITORS PROMEGA CORP (US) 2023-02-08 — — EP disclosed
US-RE49351-E1 Cytoprotective agent BIOGEN MA INC. (US) 2023-01-03 — — US disclosed
US-11124522-B2 Chemosensor and a method of detecting palladium ions KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2021-09-21 — — US disclosed
WO-2021102052-A1 DIRECTED CONJUGATION TECHNOLOGIES KLEO PHARMACEUTICALS, INC. (US) 2021-05-27 — — WO disclosed
WO-2021086917-A1 PSMA-TARGETING IMAGING AGENTS THE CLEVELAND CLINIC FOUNDATION (US) 2021-05-06 — — WO disclosed
WO-2020264327-A1 EXTRACELLULAR MATRICES, USES THEREOF, AND METHODS OF MAKING EXTRACELLULAR MATRICES GEMSTONE BIOTHERAPEUTICS LLC (US) 2020-12-30 — — WO disclosed
US-20100016416-A1 Oligonucleotide Conjugates GERON CORPORATION (US) 2010-01-21 — — US disclosed
US-7563618-B2 Oligonucleotide conjugates GERON CORPORATION (US) 2009-07-21 — — US disclosed
US-5756771-A 5(6)-methyl substituted fluorescein derivatives ABBOTT LABORATORIES (US) 1998-05-26 — — US disclosed
US-5616298-A 5(6)-methyl substituted fluorescein derivatives ABBOTT LABORATORIES (US) 1997-04-01 — — US disclosed
US-5573904-A 5(6)-Methyl substituted fluorescein derivatives ABBOTT LABORATORIES (US) 1996-11-12 — — US disclosed
US-5496925-A 5(6)-methyl substituted fluorescein derivatives ABBOTT LABORATORIES (US) 1996-03-05 — — US disclosed
EP-0635020-A1 5(6)-METHYL SUBSTITUTED FLUORESCEIN DERIVATIVES ABBOTT LABORATORIES (US) 1995-01-25 — — EP disclosed
EP-0635020-A4 5(6)-METHYL SUBSTITUTED FLUORESCEIN DERIVATIVES. ABBOTT LAB (US) 1994-12-06 — — EP disclosed
US-5352803-A 5(6)-methyl substituted fluorescein derivatives ABBOTT LABORATORIES (US) 1994-10-04 — — US disclosed
WO-1993020060-A1 5(6)-METHYL SUBSTITUTED FLUORESCEIN DERIVATIVES ABBOTT LABORATORIES (US) 1993-10-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11124522-B2 Chemosensor and a method of detecting palladium ions DDT, PDCD1, PDCD10 FTO 766/4885MAPT 2523/4885MEN1 3564/4885
US-20230286931-A1 NOVEL BENZOXAZOLE DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF TO DETECT GHB IN DRINKS AND URINE CCKBR, GABBR1, GHSR FTO 2346/4885MAPT 3761/4885MEN1 1071/4885
US-20100016416-A1 Oligonucleotide Conjugates TERT, RNGTT, TRDMT1 FTO 874/4885MAPT 1878/4885MEN1 2881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.